DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Odc1 and spe1

DIOPT Version :9

Sequence 1:	NP_477052.2	Gene:	Odc1 / 35766	FlyBaseID:	FBgn0013307	Length:	394	Species:	Drosophila melanogaster
Sequence 2:	NP_594665.1	Gene:	spe1 / 2542855	PomBaseID:	SPAC144.04c	Length:	432	Species:	Schizosaccharomyces pombe

Alignment Length:	388	Identity:	166/388 - (42%)
Similarity:	241/388 - (62%)	Gaps:	25/388 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 RRVIEECDLQRL------DQALNICDLSSVERKLRLWQKLLPRIKPFYAVKCNDDPMVVRLLAQL 76
            :..|||.:...:      ..|..:.||:.|.|:|..|...|||::||||||||.||.|:.||.:.
pombe    48 KNTIEEIERAAVRGEPADSDAFFVADLNGVYRQLLRWHAKLPRVQPFYAVKCNPDPKVLALLNKF 112

  Fly    77 GAGFDCASKNEVKLVLGFDVSPERIIFANPCRPVSHLEYAKEHQVSNGTVDNEFEVYKLHTHYPN 141
            |.|||||||.|::.:||..|||:||::||||:.::::.||....::..|.||..|:||:..|:||
pombe   113 GTGFDCASKGELEQILGLGVSPDRIVYANPCKAITYVRYAASKGINLMTFDNADELYKVKQHHPN 177

  Fly   142 SNLIVRFKSEAKEAQCPLGDKFGCDADVDAAALMLLAKSLELKVTGTSFHVGSGCSELQAYDRAI 206
            |.|::|..::...:.|.|..|||...| |...|:.:||||||.|.|.|||||||..:..|:..||
pombe   178 SRLLLRISTDDSNSLCRLSLKFGASLD-DTGKLLDIAKSLELNVVGVSFHVGSGSYDPSAFLDAI 241

  Fly   207 KKAKNLFKFGALLGYDMDFLDIGGGFPGSDDVKFEKIAESVNTSVQRHFPDERVHIIAEPGRFFV 271
            ::::.:|..|...|::.|.|||||||...   .|:.:|:.:.:::..:| |..:.:|:|||||||
pombe   242 QRSRQVFDQGLERGFNFDLLDIGGGFMND---SFDGVADLIRSALDTYF-DPSIRVISEPGRFFV 302

  Fly   272 AAACTLVCKIHAKREIRNEAGKLDTVMYYLNDGVYGSFNCILYDHQVVIAE--------HYLDNA 328
            :::.||...:.|||::.:|    :.||||:|||||||.||||:|||..:|.        .|.|..
pombe   303 SSSFTLAVNVIAKRKLDDE----EKVMYYVNDGVYGSLNCILFDHQHPVARVLKCGSRFVYNDLV 363

  Fly   329 ESLPHLKSLIWGPSCDALDKISEDLHLP-NLNRGDLLGFRNMGAYTMPIASAFNGFEVPKTLY 390
            .:..| :..||||:||:||.|:.|.||| .||.||.:.|.:.||||:..||.||||:..:.:|
pombe   364 GTGQH-RCFIWGPTCDSLDVIANDAHLPYELNVGDWIYFEDAGAYTVAAASCFNGFKTSRIVY 425

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Odc1	NP_477052.2	LysA	16..391	CDD:223098	166/388 (43%)
Odc1	NP_477052.2	PLPDE_III_ODC	30..391	CDD:143482	163/370 (44%)
spe1	NP_594665.1	LysA	40..426	CDD:223098	166/388 (43%)
spe1	NP_594665.1	PLPDE_III_ODC	67..426	CDD:143482	163/369 (44%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	208	1.000	Domainoid score	I616
eggNOG	1	0.900	-	-		E1_COG0019
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H1906
Inparanoid	1	1.050	312	1.000	Inparanoid score	I573
OMA	1	1.010	-	-		QHG62480
OrthoFinder	1	1.000	-	-		FOG0000435
OrthoInspector	1	1.000	-	-		otm47070
orthoMCL	1	0.900	-	-		OOG6_100277
Panther	1	1.100	-	-	LDO	PTHR11482
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R297
SonicParanoid	1	1.000	-	-		X335
TreeFam	1	0.960	-	-
	14	13.860