Sequence 1: | NP_523657.1 | Gene: | Hey / 35764 | FlyBaseID: | FBgn0027788 | Length: | 425 | Species: | Drosophila melanogaster |
---|---|---|---|---|---|---|---|---|---|
Sequence 2: | NP_003661.1 | Gene: | BHLHE40 / 8553 | HGNCID: | 1046 | Length: | 412 | Species: | Homo sapiens |
Alignment Length: | 460 | Identity: | 103/460 - (22%) |
---|---|---|---|
Similarity: | 157/460 - (34%) | Gaps: | 135/460 - (29%) |
- Green bases have known domain annotations that are detailed below.
Fly 39 PPPQSHHSAHSNHSHGHSQG----HSHGIGSLKRTLSESDCDDLYSEESSKEQISPSEPGSCQLM 99
Fly 100 SRKKRRGVIEKKRRDRINSSLTELKRLVPSAYEKQGSAKLEKAEILQLTVEHLKSL-------QS 157
Fly 158 KTL--------DSLSYDPQRVAMDYHIIGFRECAAEVARYLVTIEGMDIQDPLRLRLMSHLQYFV 214
Fly 215 QQRELSAKSCASPGGWSPAAPSSSGYQPNCAAAPYQSYAAPANPGAYVSSYPTLSASPSQQAQQL 279
Fly 280 GGR--TSVSRTSGSAVTESLPSHDLHSDS----SSQQQQQQQQQQQQQQQHQ------------Q 326
Fly 327 QQHQQQQQRTQTTPQPTQQQHYT------------HDHSAVHS---------------------- 357
Fly 358 EQQVPTYIELTNSNRPAAIGS----DSLSYS-AAPQYPVSGLPGQDYNNSSVLQYATPNGAKPYR 417
Fly 418 PWGAE 422 |
Gene | Sequence | Domain | Region | External ID | Identity |
---|---|---|---|---|---|
Hey | NP_523657.1 | HLH | 100..156 | CDD:238036 | 25/62 (40%) |
ORANGE | 172..218 | CDD:128787 | 14/45 (31%) | ||
BHLHE40 | NP_003661.1 | Essential for interaction with ARNTL/BMAL1, E-box binding and repressor activity against the CLOCK-ARNTL/BMAL1 heterodimer | 1..139 | 43/151 (28%) | |
bHLH-O_DEC1 | 40..129 | CDD:381592 | 33/109 (30%) | ||
Necessary for interaction with RXRA and repressor activity against RXRA. /evidence=ECO:0000269|PubMed:19786558 | 75..79 | 2/3 (67%) | |||
ORANGE | 140..184 | CDD:128787 | 14/53 (26%) | ||
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 182..303 | 21/142 (15%) |
Tool | Simple Score | Weighted Score | Original Tool Information | |||
---|---|---|---|---|---|---|
BLAST Result | Score | Score Type | Cluster ID | |||
Compara | 0 | 0.000 | Not matched by this tool. | |||
Domainoid | 0 | 0.000 | Not matched by this tool. | |||
eggNOG | 1 | 0.900 | - | - | E1_KOG4304 | |
Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
Homologene | 0 | 0.000 | Not matched by this tool. | |||
Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
Isobase | 0 | 0.000 | Not matched by this tool. | |||
OMA | 0 | 0.000 | Not matched by this tool. | |||
OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
Panther | 0 | 0.000 | Not matched by this tool. | |||
Phylome | 1 | 0.910 | - | - | ||
RoundUp | 0 | 0.000 | Not matched by this tool. | |||
SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
TreeFam | 0 | 0.000 | Not matched by this tool. | |||
User_Submission | 0 | 0.000 | Not matched by this tool. | |||
2 | 1.810 |