Protein Alignment Hey and Hes5

DIOPT Version :10

• Sequence 1: NP_523657.1
• Gene: Hey / 35764
• FlyBaseID: FBgn0027788
• Length: 425
• Species: Drosophila melanogaster
• Sequence 2: XP_038966759.1
• Gene: Hes5 / 79225
• RGDID: 621340
• Length: 196
• Species: Rattus norvegicus
• Alignment Length: 219
• Identity: 57/219 - (26%)
• Similarity: 89/219 - (40%)
• Gaps: 67/219 - (30%)

  Fly    86 EQISPSEPGSCQLMSRKKRRGVIEKKRRDRINSSLTELKRLVPSAYEK-QGSAKLEKAEILQLTV 149
            |.:||.|       ..:.|:.|:||.||||||||:.:||.|:...:.: |.::|||||:||::.|
  Rat     9 EMLSPKE-------KNRLRKPVVEKMRRDRINSSIEQLKLLLEQEFARHQPNSKLEKADILEMAV 66

  Fly   150 EHLKSLQSK---------------------------TLDSLSYDPQRVAMDYHIIGFRECAAEVA 187
            .:||..:.:                           |..:.:..|:.:..||. .|:..|..|..
  Rat    67 SYLKHSKGELGACARVLLPTGVAPTARAPLMPLGLPTAFAAAAGPKSLHQDYS-EGYSWCLQEAV 130

  Fly   188 RYLVTIEGMDIQDPLRLRLMSHLQYFVQQRELSAKSCASPGGWSPAAPSSSGYQPNCAAAPYQSY 252
            ::|......|.|    ::|:.|.|             ..|   :||||......|..|..|.:|
  Rat   131 QFLTLHAASDTQ----MKLLYHFQ-------------RPP---APAAPVKETPTPGAAPQPARS- 174

  Fly   253 AAPANPGAYVSSYPTLSASPSQQA 276
                      |:....|.|.|:|:
  Rat   175 ----------STKAAASVSTSRQS 188

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hey	NP_523657.1	bHLH_SF	95..163	CDD:469605	27/95 (28%)
		ORANGE	172..218	CDD:128787	11/45 (24%)
Hes5	XP_038966759.1	bHLH-O_HES5	18..74	CDD:381467	26/55 (47%)
		ORANGE	116..158	CDD:128787	14/62 (23%)