Protein Alignment Hey and hes1

DIOPT Version :9

• Sequence 1: NP_523657.1
• Gene: Hey / 35764
• FlyBaseID: FBgn0027788
• Length: 425
• Species: Drosophila melanogaster
• Sequence 2: NP_001011194.1
• Gene: hes1 / 496617
• XenbaseID: XB-GENE-487995
• Length: 267
• Species: Xenopus tropicalis
• Alignment Length: 362
• Identity: 97/362 - (26%)
• Similarity: 143/362 - (39%)
• Gaps: 117/362 - (32%)

  Fly    77 DLYSEESSKE--------QISPSEPGSCQLMSRKKRRGVIEKKRRDRINSSLTELKRLVPSAYEK 133
            ||..:.||..        ..:|.:|.:.. ..||..:.::||:||.|||.||.:||.|:..|.:|
 Frog     4 DLMEKNSSSPVAATPASMSNTPDKPKTAS-EHRKSSKPIMEKRRRARINESLGQLKTLILDALKK 67

  Fly   134 QGS--AKLEKAEILQLTVEHLKSLQSKTLD-SLSYDPQRVAMDYHIIGFRECAAEVARYLVTIEG 195
            ..|  :|||||:||::||:||::||...:. :||.||.  .:..:..||.||..||.|:|.|.||
 Frog    68 DSSRHSKLEKADILEMTVKHLRNLQRVQMTAALSTDPS--VLGKYRAGFSECMNEVTRFLSTCEG 130

  Fly   196 MDIQDPLRLRLMSHLQYFVQQRELSAKSCASPGGWSPAAPSSSGYQPNCAAAPYQSYAAP--ANP 258
              :...:|.||:.||...:.|  ::|.:       .|..|     |...||||:.:|..|  ...
 Frog   131 --VNTDVRTRLLGHLANCMNQ--INAMN-------YPTQP-----QIPAAAAPHPAYGQPLVQLQ 179

  Fly   259 GAYVSSYPT-----LSASPSQQAQQLGGRTSVSRTSGSAVTESLPSHDLHSDSSSQQQQQQQQQQ 318
            ||...|.|.     :...|.:.|:..||
 Frog   180 GAAPQSSPAPIACKMGGPPVEAAKVYGG------------------------------------- 207

  Fly   319 QQQQQHQQQQHQQQQQRTQTTPQPTQQQHYTHDHSAV-HSEQQVPTYIELTNSNRPAAIGSDSLS 382
                             .|..|.|..|..:...:.|. |:...:|.|   ||||    :|: :|.
 Frog   208 -----------------FQLVPAPDGQFAFLITNPAFPHNGSVIPVY---TNSN----VGT-ALP 247

  Fly   383 YSAAPQYPVSGLPGQDYNNSSVLQYATPNGAKPYRPW 419
            .|.:|               ||:...|.:..  :|||
 Frog   248 PSVSP---------------SVMPSVTADSV--WRPW 267

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hey	NP_523657.1	HLH	100..156	CDD:238036	28/57 (49%)
		ORANGE	172..218	CDD:128787	17/45 (38%)
hes1	NP_001011194.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..45		9/41 (22%)
		bHLH-O_HES1_4	33..95	CDD:381465	30/61 (49%)
		Hairy_orange	110..148	CDD:369405	16/39 (41%)
		WRPW motif. /evidence=ECO:0000255	264..267		1/2 (50%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910