DRSC/TRiP Functional Genomics Resources

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Protein Alignment Hey and cwo

DIOPT Version :9

Sequence 1:NP_523657.1 Gene:Hey / 35764 FlyBaseID:FBgn0027788 Length:425 Species:Drosophila melanogaster
Sequence 2:NP_524775.1 Gene:cwo / 44669 FlyBaseID:FBgn0259938 Length:698 Species:Drosophila melanogaster


Alignment Length:415 Identity:93/415 - (22%)
Similarity:156/415 - (37%) Gaps:127/415 - (30%)


- Green bases have known domain annotations that are detailed below.


  Fly    50 NHSHGHSQGHSH--------GIGSL----KRTLSESDCDDLYSEESS------KEQISPSEPGSC 96
            |.::||:   :|        .:.|.    :.:|:.|.....|||:.:      :.:.|..:|   
  Fly     6 NETNGHA---AHPVKYESEAAVSSFPYCTESSLNFSTSATAYSEDDAEYATGRRNKTSRQDP--- 64

  Fly    97 QLMSRKKRRGVIEKKRRDRINSSLTELKRLVPSAYEKQGSAKLEKAEILQLTVEHLKSLQSKTLD 161
              :|.:    :|||:||||:||.|.:|.||:|..|:::|..::||.||:::.:.|||.|||:.  
  Fly    65 --LSHR----IIEKRRRDRMNSCLADLSRLIPPQYQRKGRGRIEKTEIIEMAIRHLKHLQSEC-- 121

  Fly   162 SLSYDPQRVAMDYHIIGFRECAAEVARYLVTIEGMDIQDPLRLRLMSHL-QYFVQQRELSAKSCA 225
                  |:...||. .|:.:|..|.|::|..:...|....|..||..|: :.|......|.:||.
  Fly   122 ------QQKESDYR-SGYMDCMKEAAKFLYDVHMQDFCHRLLGRLQEHIDEMFKTDCYKSTRSCH 179

  Fly   226 SPGGWSPAAPSSSGYQPNCAAAPYQSYAAP----------------------------------- 255
            .|...|    :|||       :|:|:|..|                                   
  Fly   180 MPDNVS----ASSG-------SPHQAYHPPLCHLRDMLATSASDVEHSQDHNDVKDLSFRNHLNQ 233

  Fly   256 ------ANPGAYVSSYPTLSASPSQQAQQLGGRTSVSRTSGSA------VTESLPSHDLHSDSSS 308
                  |...|.|::.....|:.|..|...|..:.|..|:|..      ..:::||:...|.|::
  Fly   234 LQRSQQAAAAAAVAAAAVAVANGSSPASNAGVDSKVPLTNGGGTGGAPPAADNVPSNSTGSGSAA 298

  Fly   309 QQQQQQQQQQQQQQQHQQQQ-------------------HQQQQQR---TQTTPQPTQQQHYTHD 351
            ...............:....                   |||..|.   |.|.|    ..|:.|.
  Fly   299 ACAGGNSNSSGSNSSNAASSTICPPAGGSCPAKVTPLAAHQQPHQAPVITSTAP----HHHHHHT 359

  Fly   352 HSAVH---SEQQVPTYIELTNSNRP 373
            .|:.|   |.::...:.:.:|.:.|
  Fly   360 DSSHHDFESSREPILHTDTSNMHSP 384

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
HeyNP_523657.1 HLH 100..156 CDD:238036 24/55 (44%)
ORANGE 172..218 CDD:128787 13/46 (28%)
cwoNP_524775.1 HLH 66..118 CDD:306515 24/55 (44%)
ORANGE 126..168 CDD:128787 12/42 (29%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 1 1.000 45 1.000 Domainoid score I4621
eggNOG 1 0.900 - - E1_KOG4304
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - P PTHR10985
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
43.910

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