Protein Alignment Hey and HES3

DIOPT Version :9

• Sequence 1: NP_523657.1
• Gene: Hey / 35764
• FlyBaseID: FBgn0027788
• Length: 425
• Species: Drosophila melanogaster
• Sequence 2: NP_001019769.1
• Gene: HES3 / 390992
• HGNCID: 26226
• Length: 186
• Species: Homo sapiens
• Alignment Length: 211
• Identity: 70/211 - (33%)
• Similarity: 96/211 - (45%)
• Gaps: 40/211 - (18%)

  Fly   108 IEKKRRDRINSSLTELKRLVPSAYEKQ-GSAKLEKAEILQLTVEHLKSLQSKTLDSLSYDPQRVA 171
            :|||||.|||.||.:||.|:...|..| ...|||||:||:|:|::::|||: :|..|...|:...
Human     1 MEKKRRARINVSLEQLKSLLEKHYSHQIRKRKLEKADILELSVKYMRSLQN-SLQGLWPVPRGAE 64

  Fly   172 MDYHIIGFRECAAEVARYLVTIEGMDIQDPLRLRLMSHLQYFVQQRELSAKSCASPGGWSPAAPS 236
            ..   .|||.|...|::.|  ..|.::...||..|:.         |.:|.|.....|....||:
Human    65 QP---SGFRSCLPGVSQLL--RRGDEVGSGLRCPLVP---------ESAAGSTMDSAGLGQEAPA 115

  Fly   237 SSGYQPNCAA--APYQSYAAPANPGAYV---SSYPTLSAS--PSQQAQQ-------LGGRTSVSR 287
            .  ::|...|  ||..:...|.:|...:   .|.|..|||  |.|.|..       ||.|  |.|
Human   116 L--FRPCTPAVWAPAPAAGGPRSPPPLLLLPESLPGSSASVPPPQPASSRCAESPGLGLR--VWR 176

  Fly   288 TSGSAVTESLPSHDLH 303
            ..||      |..||:
Human   177 PWGS------PGDDLN 186

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hey	NP_523657.1	HLH	100..156	CDD:238036	25/48 (52%)
		ORANGE	172..218	CDD:128787	10/45 (22%)
HES3	NP_001019769.1	HLH	1..54	CDD:238036	27/53 (51%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	128..186		19/65 (29%)
		WRPW motif	175..178		1/2 (50%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4304
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810