Protein Alignment Dic3 and SLC25A27

DIOPT Version :9

• Sequence 1: NP_610344.2
• Gene: Dic3 / 35763
• FlyBaseID: FBgn0033248
• Length: 287
• Species: Drosophila melanogaster
• Sequence 2: NP_004268.3
• Gene: SLC25A27 / 9481
• HGNCID: 21065
• Length: 323
• Species: Homo sapiens
• Alignment Length: 319
• Identity: 90/319 - (28%)
• Similarity: 149/319 - (46%)
• Gaps: 38/319 - (11%)

  Fly     3 EDSSRRLP---RW------WFGGVCAAIAVTGTHPIDLIKVQLQTQSQADRKTVGEILK------ 52
            |:..|.||   ||      ...|..|.:|...|.|:||.|.:||.|.:|....:|:..:
Human     5 EEEERLLPLTQRWPRASKFLLSGCAATVAELATFPLDLTKTRLQMQGEAALARLGDGARESAPYR 69

  Fly    53 -------GIHERSGILGFYNGISASWFRQLTYTTTRFALYE------AGKDYVDTQKVSSKMALA 104
                   ||.|..|.|..:.|::.:.:|.:.|:..|...||      .||...:...:...:...
Human    70 GMVRTALGIIEEEGFLKLWQGVTPAIYRHVVYSGGRMVTYEHLREVVFGKSEDEHYPLWKSVIGG 134

  Fly   105 TFAGIVGGIVGVPGDVVTVRLQNDVKLP-EEKRRNYKHVFDGLFRIYKEEGVSSLFRGTVPAVSR 168
            ..||::|..:..|.|:|.|::|.:.|.. |.|...::.|.....:|..|.|:..|:.|.||.:.|
Human   135 MMAGVIGQFLANPTDLVKVQMQMEGKRKLEGKPLRFRGVHHAFAKILAEGGIRGLWAGWVPNIQR 199

  Fly   169 AVLLTIGTNAAYDQVKQMLKIATGAGEGVPLHFATSTIAGCIAVVITQPLDVIKTTFMNAQPGEF 233
            |.|:.:|....||.||..|.:.|...:.:..|..:|..:|.:|.::..|.||||:..|| ||.:.
Human   200 AALVNMGDLTTYDTVKHYLVLNTPLEDNIMTHGLSSLCSGLVASILGTPADVIKSRIMN-QPRDK 263

  Fly   234 SGIGGAFLSTAK--------QGPLAFYKGFIPALIRVSPNTIITFVLYEQARMRFGYLP 284
            .|.|..:.|:..        :|.::.||||:|:.:|::|.:::.::.||:.|...|..|
Human   264 QGRGLLYKSSTDCLIQAVQGEGFMSLYKGFLPSWLRMTPWSMVFWLTYEKIREMSGVSP 322

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dic3	NP_610344.2	PTZ00169	15..275	CDD:240302	80/287 (28%)
		Mito_carr	15..91	CDD:278578	26/94 (28%)
		Mito_carr	93..187	CDD:278578	27/94 (29%)
		Mito_carr	200..281	CDD:278578	27/88 (31%)
SLC25A27	NP_004268.3	Mito_carr	20..118	CDD:365909	24/97 (25%)
		Solcar 1	21..115		24/93 (26%)
		Mito_carr	125..219	CDD:365909	27/93 (29%)
		Solcar 2	125..217		27/91 (30%)
		Solcar 3	226..317		27/91 (30%)
		Mito_carr	227..317	CDD:365909	27/90 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0759
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810