Protein Alignment Dic3 and SLC25A14

DIOPT Version :10

• Sequence 1: NP_610344.2
• Gene: Dic3 / 35763
• FlyBaseID: FBgn0033248
• Length: 287
• Species: Drosophila melanogaster
• Sequence 2: NP_001269126.1
• Gene: SLC25A14 / 9016
• HGNCID: 10984
• Length: 353
• Species: Homo sapiens
• Alignment Length: 318
• Identity: 83/318 - (26%)
• Similarity: 135/318 - (42%)
• Gaps: 65/318 - (20%)

  Fly    14 FGGVCAAIAVTGTHPIDLIKVQLQTQSQADRKTVGEI--------LKGIHERSGILGFYNGISAS 70
            :||:.:.:|..||.|:||.|.:||.|.|:......||        |..|.:..|:|..|:||:.:
Human    43 YGGLASIVAEFGTFPVDLTKTRLQVQGQSIDARFKEIKYRGMFHALFRICKEEGVLALYSGIAPA 107

  Fly    71 WFRQLTYTTTRFALYEAGK----DYVDTQKVSSKMALATFAGIVGGIVGVPGDVVTVRLQNDVKL 131
            ..||.:|.|.:..:|::.|    :.::.:.:...|.....:|::...:..|.||:.:|:|....|
Human   108 LLRQASYGTIKIGIYQSLKRLFVERLEDETLLINMICGVVSGVISSTIANPTDVLKIRMQAQGSL 172

  Fly   132 PEEKRRNYKHVFDG-----LFRIYKEEGVSSLFR------------------------------- 160
                       |.|     ...||::||...|:|
Human   173 -----------FQGSMIGSFIDIYQQEGTRGLWRCLCSKAVTGCVLWLMPVIPALWEANAGGSLE 226

  Fly   161 GTVPAVSRAVLLTIGTNAAYDQVKQMLKIATGAGEGVPLHFATSTIAGCIAVVITQPLDVIKTTF 225
            |.||...||.::.......||..|:.|.::...|:.:..||.:|...|....:.:.|:||::|..
Human   227 GVVPTAQRAAIVVGVELPVYDITKKHLILSGMMGDTILTHFVSSFTCGLAGALASNPVDVVRTRM 291

  Fly   226 MN--AQPGE---FSG-IGGAFLSTAKQGPLAFYKGFIPALIRVSPNTIITFVLYEQAR 277
            ||  |..|.   :.| :.|.......:|..|.||||.|..:|:.|..||.|:.|||.:
Human   292 MNQRAIVGHVDLYKGTVDGILKMWKHEGFFALYKGFWPNWLRLGPWNIIFFITYEQLK 349

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dic3	NP_610344.2	Mito_carr	15..91	CDD:395101	28/87 (32%)
		Mito_carr	93..187	CDD:395101	24/129 (19%)
		Mito_carr	200..281	CDD:395101	29/84 (35%)
SLC25A14	NP_001269126.1	Mito_carr	37..133	CDD:395101	28/89 (31%)
		Mito_carr	134..254	CDD:395101	24/130 (18%)
		Mito_carr	262..351	CDD:395101	29/88 (33%)