Protein Alignment Dic3 and SLC25A11

DIOPT Version :10

• Sequence 1: NP_610344.2
• Gene: Dic3 / 35763
• FlyBaseID: FBgn0033248
• Length: 287
• Species: Drosophila melanogaster
• Sequence 2: NP_003553.2
• Gene: SLC25A11 / 8402
• HGNCID: 10981
• Length: 314
• Species: Homo sapiens
• Alignment Length: 286
• Identity: 94/286 - (32%)
• Similarity: 147/286 - (51%)
• Gaps: 16/286 - (5%)

  Fly     5 SSRRLPRWWFGGVCAAIAVTGTHPIDLIKVQLQTQSQA----DRKTVGEILKGIHERSGILGFYN 65
            :|.:..::.|||:....|.....|:||:|.::|...:.    :.||....|..|.:..|:.|.|.
Human    18 TSPKSVKFLFGGLAGMGATVFVQPLDLVKNRMQLSGEGAKTREYKTSFHALTSILKAEGLRGIYT 82

  Fly    66 GISASWFRQLTYTTTRFALYE------AGKDYVDTQKVSSKMALATFAGIVGGIVGVPGDVVTVR 124
            |:||...||.||||||..:|.      .|.|......: .|..:...||..|..||.|.:|..:|
Human    83 GLSAGLLRQATYTTTRLGIYTVLFERLTGADGTPPGFL-LKAVIGMTAGATGAFVGTPAEVALIR 146

  Fly   125 LQNDVKLPEEKRRNYKHVFDGLFRIYKEEGVSSLFRGTVPAVSRAVLLTIGTNAAYDQVKQMLKI 189
            :..|.:||.::||.||:||:.|.||.:||||.:|:||.:|.::|||::.....|:|.|.||.|..
Human   147 MTADGRLPADQRRGYKNVFNALIRITREEGVLTLWRGCIPTMARAVVVNAAQLASYSQSKQFLLD 211

  Fly   190 ATGAGEGVPLHFATSTIAGCIAVVITQPLDVIKTTFMN-----AQPGEFSGIGGAFLSTAKQGPL 249
            :....:.:..||..|.|:|.:....:.|:|:.||...|     .:|...:|:...|.....:|..
Human   212 SGYFSDNILCHFCASMISGLVTTAASMPVDIAKTRIQNMRMIDGKPEYKNGLDVLFKVVRYEGFF 276

  Fly   250 AFYKGFIPALIRVSPNTIITFVLYEQ 275
            :.:|||.|...|:.|:|::||:..||
Human   277 SLWKGFTPYYARLGPHTVLTFIFLEQ 302

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dic3	NP_610344.2	Mito_carr	15..91	CDD:395101	28/85 (33%)
		Mito_carr	93..187	CDD:395101	37/93 (40%)
		Mito_carr	200..281	CDD:395101	25/81 (31%)
SLC25A11	NP_003553.2	Solcar 1	23..108		28/84 (33%)
		Mito_carr	24..102	CDD:395101	27/77 (35%)
		Mito_carr	116..213	CDD:395101	38/97 (39%)
		Solcar 2	117..208		36/91 (40%)
		Mito_carr	215..309	CDD:395101	25/88 (28%)
		Solcar 3	217..306		25/86 (29%)