Protein Alignment Dic3 and UCP3

DIOPT Version :9

• Sequence 1: NP_610344.2
• Gene: Dic3 / 35763
• FlyBaseID: FBgn0033248
• Length: 287
• Species: Drosophila melanogaster
• Sequence 2: NP_003347.1
• Gene: UCP3 / 7352
• HGNCID: 12519
• Length: 312
• Species: Homo sapiens
• Alignment Length: 280
• Identity: 95/280 - (33%)
• Similarity: 138/280 - (49%)
• Gaps: 20/280 - (7%)

  Fly    16 GVCAAIAVTGTHPIDLIKVQLQTQSQAD----------RKTVGEILKGIHERSGILGFYNGISAS 70
            |..|..|...|.|:|..||:||.|.:..          |..:|.||..: ...|....|||:.|.
Human    21 GTAACFADLVTFPLDTAKVRLQIQGENQAVQTARLVQYRGVLGTILTMV-RTEGPCSPYNGLVAG 84

  Fly    71 WFRQLTYTTTRFALYEAGKDYVDTQKVSSKMALAT--FAGIVGGIVGV----PGDVVTVRLQNDV 129
            ..||:::.:.|..||::.|. |.|.|.:...:|.|  .||...|.:.|    |.|||.||.|..:
Human    85 LQRQMSFASIRIGLYDSVKQ-VYTPKGADNSSLTTRILAGCTTGAMAVTCAQPTDVVKVRFQASI 148

  Fly   130 KL-PEEKRRNYKHVFDGLFRIYKEEGVSSLFRGTVPAVSRAVLLTIGTNAAYDQVKQMLKIATGA 193
            .| |....|.|....|....|.:||||..|::||:|.:.|..::.......||.:|:.|......
Human   149 HLGPSRSDRKYSGTMDAYRTIAREEGVRGLWKGTLPNIMRNAIVNCAEVVTYDILKEKLLDYHLL 213

  Fly   194 GEGVPLHFATSTIAGCIAVVITQPLDVIKTTFMNAQPGE-FSGIGGAFLSTAKQGPLAFYKGFIP 257
            .:..|.||.::..||..|.|:..|:||:||.:||:.||: ||.:.......|::||.||||||.|
Human   214 TDNFPCHFVSAFGAGFCATVVASPVDVVKTRYMNSPPGQYFSPLDCMIKMVAQEGPTAFYKGFTP 278

  Fly   258 ALIRVSPNTIITFVLYEQAR 277
            :.:|:....::.||.|||.:
Human   279 SFLRLGSWNVVMFVTYEQLK 298

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dic3	NP_610344.2	PTZ00169	15..275	CDD:240302	93/276 (34%)
		Mito_carr	15..91	CDD:278578	26/84 (31%)
		Mito_carr	93..187	CDD:278578	33/100 (33%)
		Mito_carr	200..281	CDD:278578	33/79 (42%)
UCP3	NP_003347.1	Mito_carr	10..110	CDD:278578	28/90 (31%)
		Solcar 1	11..105		26/85 (31%)
		PTZ00169	14..302	CDD:240302	95/280 (34%)
		Mito_carr	112..210	CDD:278578	32/97 (33%)
		Solcar 2	114..206		31/91 (34%)
		Mito_carr	214..303	CDD:278578	34/85 (40%)
		Solcar 3	215..300		34/84 (40%)
		Purine nucleotide binding. /evidence=ECO:0000250	279..301		6/20 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0759
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D984118at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820