DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Dic3 and slc25a10b

DIOPT Version :9

Sequence 1:	NP_610344.2	Gene:	Dic3 / 35763	FlyBaseID:	FBgn0033248	Length:	287	Species:	Drosophila melanogaster
Sequence 2:	NP_957466.1	Gene:	slc25a10b / 394147	ZFINID:	ZDB-GENE-040426-1095	Length:	286	Species:	Danio rerio

Alignment Length:	285	Identity:	135/285 - (47%)
Similarity:	182/285 - (63%)	Gaps:	13/285 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 SSRRLPRWWFGGVCAAIAVTGTHPIDLIKVQLQTQSQADRKTVGEILKGIH--ERSGILGFYNGI 67
            :.:|:.||:|||:.:..|...|||:|||||.||||.:...:.:|   ..||  :..|.|..|:|:
Zfish     2 AEKRMSRWYFGGIASCGAACCTHPLDLIKVHLQTQQEVKMRMMG---MAIHVVKNDGFLALYSGL 63

  Fly    68 SASWFRQLTYTTTRFALYEAGKDYVDT-----QKVSSKMALATFAGIVGGIVGVPGDVVTVRLQN 127
            |||..||::|:.||||:||..:|.:.:     .....|:.|..|.|..||.:|.|.|:|.||:||
Zfish    64 SASLCRQMSYSLTRFAIYETVRDTLGSGSQGPMPFYQKVLLGAFGGFTGGFIGTPADMVNVRMQN 128

  Fly   128 DVKLPEEKRRNYKHVFDGLFRIYKEEGVSSLFRGTVPAVSRAVLLTIGTNAAYDQVKQMLKIATG 192
            |||||.|:||||||..|||||:::|||...||.|...|.||..|:|:|..|.|||.||:: :.||
Zfish   129 DVKLPLEQRRNYKHALDGLFRVWREEGTRRLFSGATMASSRGALVTVGQLACYDQAKQLV-LGTG 192

  Fly   193 -AGEGVPLHFATSTIAGCIAVVITQPLDVIKTTFMNAQPGEFSGIGGAFLSTAKQGPLAFYKGFI 256
             .|:.:..||.:|.|||..|..:.|||||:||..||:: ||:.|:......|||.||||||||.:
Zfish   193 LMGDNILTHFLSSFIAGGCATFLCQPLDVLKTRLMNSK-GEYRGVMHCLSETAKLGPLAFYKGLV 256

  Fly   257 PALIRVSPNTIITFVLYEQARMRFG 281
            ||.||:.|:||:|||..||.:..||
Zfish   257 PAGIRLIPHTILTFVFLEQLKKYFG 281

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dic3	NP_610344.2	PTZ00169	15..275	CDD:240302	127/267 (48%)
		Mito_carr	15..91	CDD:278578	34/77 (44%)
		Mito_carr	93..187	CDD:278578	49/98 (50%)
		Mito_carr	200..281	CDD:278578	42/80 (53%)
slc25a10b	NP_957466.1	PTZ00169	12..278	CDD:240302	129/270 (48%)
		Mito_carr	12..92	CDD:278578	35/82 (43%)
		Mito_carr	<118..190	CDD:278578	42/72 (58%)
		Mito_carr	197..281	CDD:278578	42/84 (50%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170594911
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0759
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG51917
OrthoDB	1	1.010	-	-		D404074at33208
OrthoFinder	1	1.000	-	-		FOG0002037
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_104245
Panther	1	1.100	-	-	O	PTHR45618
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1953
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	11	10.720