Protein Alignment Dic3 and Tyler

DIOPT Version :10

• Sequence 1: NP_610344.2
• Gene: Dic3 / 35763
• FlyBaseID: FBgn0033248
• Length: 287
• Species: Drosophila melanogaster
• Sequence 2: NP_608327.2
• Gene: Tyler / 3772349
• FlyBaseID: FBgn0031038
• Length: 441
• Species: Drosophila melanogaster
• Alignment Length: 388
• Identity: 79/388 - (20%)
• Similarity: 134/388 - (34%)
• Gaps: 139/388 - (35%)

  Fly    15 GGVCAAIAVTGTHPIDLIKVQLQTQ-SQADRKTVGEI---------------------------- 50
            ||:.....||   |::::|.::||| :...|.||.::
  Fly    55 GGLITTFVVT---PLEVVKTRVQTQHAIRQRPTVSKLCYVYHNGLMTHVCRSSDICVPKPGRDPQ 116

  Fly    51 ----LKGIHE-------RSGILGFYNGISASWFRQLTYTTTRFALYEAGKD-----YVDTQK--- 96
                |:|..:       .||..|.:.|:|.:....|..|...|..||..|:     |:.:||
  Fly   117 NLRPLRGAMDAFVKIVCTSGFSGLWAGLSPTLVSALPSTIIYFLTYEYIKNSLSHIYLVSQKFEE 181

  Fly    97 ------------------------VSSKMALAT-----FAGIVGGIVG--------VPGDVVTVR 124
                                    ||:...::|     :..:..||..        .|.::|.::
  Fly   182 SGMKDQVPGADGGDPLDQATRGINVSATAPVSTASLPYYVPMASGICSRTIVVTAITPIEMVRIK 246

  Fly   125 LQNDVKLPEEKRRNYKHVFDGLFRIYKEEGVSSLFRGTVPAVSRAVLLTIGTN-AAYDQVKQMLK 188
            :|::.       ..|..::..|..:.::.|:..|:||..|.|.|....: ||. |.|:.:|:...
  Fly   247 MQSEY-------MTYAELWRVLRSLIRQHGILGLWRGWPPTVMRDAPFS-GTYWAVYEAIKRAFS 303

  Fly   189 IATGAGEGVP---LHFATSTIAGCIAVVITQPLDVIKT------------TFMNAQPGEFSGIG- 237
            :..      |   ..|.|..|:|.:|..:|.|.|:|.|            ..:.|..|..:|.|
  Fly   304 VTE------PTFLFSFLTGAISGAVATFVTMPFDLITTHTQIELGQDVLYEEIGAGTGAGTGTGA 362

  Fly   238 GAFLSTAK--------------------QGPLAFYKGFIPALIRVSPNTIITFVLYEQARMRF 280
            ||...|.:                    ||....|.|.:|.::||.|...|....:|.::..|
  Fly   363 GARPKTPQSAVANSRPSVLSRMRQIYRLQGVRGLYVGVMPRMLRVVPACAIMISTFEYSKSFF 425

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dic3	NP_610344.2	Mito_carr	15..91	CDD:395101	25/120 (21%)
		Mito_carr	93..187	CDD:395101	24/134 (18%)
		Mito_carr	200..281	CDD:395101	28/114 (25%)
Tyler	NP_608327.2	Mito_carr	41..171	CDD:395101	25/118 (21%)
		Mito_carr	216..303	CDD:395101	19/94 (20%)
		Mito_carr	306..429	CDD:395101	29/126 (23%)