Protein Alignment Dic3 and SLC25A34

DIOPT Version :10

• Sequence 1: NP_610344.2
• Gene: Dic3 / 35763
• FlyBaseID: FBgn0033248
• Length: 287
• Species: Drosophila melanogaster
• Sequence 2: NP_997231.1
• Gene: SLC25A34 / 284723
• HGNCID: 27653
• Length: 304
• Species: Homo sapiens
• Alignment Length: 304
• Identity: 77/304 - (25%)
• Similarity: 128/304 - (42%)
• Gaps: 56/304 - (18%)

  Fly    15 GGVCAAIAVTGTHPIDLIKVQLQTQSQADRKTVGEI-LKGIHER---------------SGILGF 63
            |.....:|...|:|::::|.:||.|        ||: .:|.:.|               .|:.|.
Human    13 GASACCLACVFTNPLEVVKTRLQLQ--------GELQARGTYPRPYHGFIASVAAVARADGLWGL 69

  Fly    64 YNGISASWFRQLTYTTTRFALYEAGKDYVDTQKVSSKMALATFAGIVGGIVGVPGDVVTVRLQND 128
            ..|::|....|......||..|........||:....:.....||.:|..||.|..::..:||..
Human    70 QKGLAAGLLYQGLMNGVRFYCYSLACQAGLTQQPGGTVVAGAVAGALGAFVGSPAYLIKTQLQAQ 134

  Fly   129 --VKLPEEKRRNYKHVFDGLFRIYKEEGVSSLFR---GTVPAV---SRAVLLTIGTNAAYDQVKQ 185
              ..:....:.|::.|...|..|::::|:..|::   |.||.|   |.|.|.|..:..|:.|.:|
Human   135 TVAAVAVGHQHNHQTVLGALETIWRQQGLLGLWQGVGGAVPRVMVGSAAQLATFASAKAWVQKQQ 199

  Fly   186 MLK-----IATGAGEGVPLHFATSTIAGCIAVVITQPLDVIKTTFMNAQPGEFSGIGGAFLSTA- 244
            .|.     :|...|          .|:....||:..|.||:.|...| ||.:.:|.|..:....
Human   200 WLPEDSWLVALAGG----------MISSIAVVVVMTPFDVVSTRLYN-QPVDTAGRGQLYGGLTD 253

  Fly   245 -------KQGPLAFYKGFIPALIRVSPNTIITFVLYEQARMRFG 281
                   ::||||.|||..||.:|:.|:||::.:.:::.|...|
Human   254 CMVKIWRQEGPLALYKGLGPAYLRLGPHTILSMLFWDELRKLAG 297

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dic3	NP_610344.2	Mito_carr	15..91	CDD:395101	20/91 (22%)
		Mito_carr	93..187	CDD:395101	27/101 (27%)
		Mito_carr	200..281	CDD:395101	26/88 (30%)
SLC25A34	NP_997231.1	Mito_carr	2..91	CDD:395101	19/85 (22%)
		Solcar 1	4..97		20/91 (22%)
		Solcar 2	101..194		23/92 (25%)
		Mito_carr	<119..197	CDD:395101	20/77 (26%)
		Mito_carr	203..295	CDD:395101	28/102 (27%)
		Solcar 3	204..295		28/101 (28%)