DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Nup44A and AT2G30050

DIOPT Version :9

Sequence 1:	NP_610343.1	Gene:	Nup44A / 35762	FlyBaseID:	FBgn0033247	Length:	354	Species:	Drosophila melanogaster
Sequence 2:	NP_180566.1	Gene:	AT2G30050 / 817556	AraportID:	AT2G30050	Length:	302	Species:	Arabidopsis thaliana

Alignment Length:	323	Identity:	93/323 - (28%)
Similarity:	150/323 - (46%)	Gaps:	52/323 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 EPIIADHKDVIHDVVFDYYGRRMATCSSDQTVKIWDEDGQGKWNVTSSWKAHSGSIWRVSWAHPE 69
            :.|...|:|::|||..||||:|:||.|||.|:||......|.....::...|.|.:|.|:||||:
plant     4 QKIETGHEDIVHDVQMDYYGKRIATASSDCTIKITGVSNNGGSQQLATLTGHRGPVWEVAWAHPK 68

  Fly    70 FGQVVATCSFDRTASVWEEVIGEKVSSTNTPTRRWVRRTTLVDSRTSVTDVEFAPKYLGLLLATA 134
            :|.::|:||:|....:|:|  |.:        .:|.:.....|.::||..:.:||..:||.||..
plant    69 YGSILASCSYDGQVILWKE--GNQ--------NQWTQDHVFTDHKSSVNSIAWAPHDIGLSLACG 123

  Fly   135 SADGIIRIYEAP-----DIMNLSQWPVQHEISNKLPLSCLSWNTSTY-----------MVTQLLA 183
            |:||.|.::.|.     |...:.|       ::.:.::.:||..:|.           .|.:|.:
plant   124 SSDGNISVFTARADGGWDTSRIDQ-------AHPVGVTSVSWAPATAPGALVSSGLLDPVYKLAS 181

  Fly   184 AGSDEAATPTGKVFLFAYSENSRKCVKIDTVNDITDPVTDVAFAPNAGRTFHMLAVASKD----L 244
            .|.|.    |.||:..|.......|  ...:...||.|.|||:|||.|.....:|..|:|    :
plant   182 GGCDN----TVKVWKLANGSWKMDC--FPALQKHTDWVRDVAWAPNLGLPKSTIASGSQDGKVII 240

  Fly   245 YIVNLRGVTDATDISKLDIQTIKFSEHNCPVWRVCWNMLATMLISTGDDGCVRLWRMNYNRQW 307
            :.|...|......:.| |..|        |||||.|::...:|..:..:..|.:|:...:.:|
plant   241 WTVGKEGEQWEGKVLK-DFMT--------PVWRVSWSLTGNLLAVSDGNNNVTVWKEAVDGEW 294

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Nup44A	NP_610343.1	WD40	11..300	CDD:392136	90/308 (29%)
		WD40 repeat	16..55	CDD:293791	17/38 (45%)
		WD40 repeat	60..98	CDD:293791	14/37 (38%)
		WD40 repeat	118..159	CDD:293791	13/45 (29%)
		WD40 repeat	166..212	CDD:293791	12/56 (21%)
		WD40 repeat	221..267	CDD:293791	16/49 (33%)
		WD40 repeat	275..299	CDD:293791	7/23 (30%)
AT2G30050	NP_180566.1	WD40	8..287	CDD:421866	90/310 (29%)
		WD40 repeat	60..101	CDD:293791	15/50 (30%)
		WD40 repeat	106..146	CDD:293791	13/39 (33%)
		WD40 repeat	154..201	CDD:293791	11/50 (22%)
		WD40 repeat	213..254	CDD:293791	13/40 (33%)
		WD40 repeat	262..288	CDD:293791	8/25 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D944756at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920