DRSC/TRiP Functional Genomics Resources

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Protein Alignment Nup44A and seh1

DIOPT Version :10

Sequence 1:NP_610343.1 Gene:Nup44A / 35762 FlyBaseID:FBgn0033247 Length:354 Species:Drosophila melanogaster
Sequence 2:NP_593751.1 Gene:seh1 / 2541682 PomBaseID:SPAC15F9.02 Length:339 Species:Schizosaccharomyces pombe


Alignment Length:340 Identity:120/340 - (35%)
Similarity:187/340 - (55%) Gaps:45/340 - (13%)


- Green bases have known domain annotations that are detailed below.


  Fly     7 IIADHKDVIHDVVFDYYGRRMATCSSDQTVKIWD-EDGQGKWNVTSSWKAHSGSIWRVSWAHPEF 70
            |..:|:|:::||.:|:|||||.:||:||.||::| .|....|.:||.|:|...|:.||:||||.|
pombe     9 IQTNHQDLVNDVTYDFYGRRMVSCSADQRVKVYDFNDDTETWAITSEWRAGDASLMRVAWAHPSF 73

  Fly    71 GQVVATCSFDRTASVWEEVIGEKVSSTNTPTRRWVRRTTLVDSRTSVTDVEFAPKYLGLLLATAS 135
            |||:|.||.||...::||      ...|..::.||....|:|:|::|.|:.|.|...|..||..|
pombe    74 GQVLAVCSLDRGVRIYEE------QKKNFESKTWVEVAKLMDARSAVLDISFCPFQHGCKLAAVS 132

  Fly   136 ADGIIRIYEAPDIMNLSQWPVQHEIS--------NKLPLSCLSWNTSTYMVTQLLAAGSDEAATP 192
            ||..:|||||.:..||:.|.:.:||:        |:.|..|::|..|.:. .|.:|.|....|  
pombe   133 ADATLRIYEAMEPGNLTYWTLMNEIALMPSPPSRNEQPAFCVNWCPSRWR-EQYIAVGCMNDA-- 194

  Fly   193 TGKVFLFAYSENSR-KCVKIDTVNDITDPVTDVAFAPNAGRTFHMLAVASKDLYIVNLRGVT--- 253
                  :.|.:||. |..|:..:...||.:.|:.:||:.|.:::::|.|.||..:...:..|   
pombe   195 ------YIYKQNSHGKWKKVAELPGHTDLIRDICWAPSMGSSYYLIATACKDGNVRIFKVETLCE 253

  Fly   254 -------DA----TDISKLDIQTIK------FSEHNCPVWRVCWNMLATMLISTGDDGCVRLWRM 301
                   ||    |:.|..::.::|      :..|.|.|||..:|:..|:|.|:|||||||||:.
pombe   254 EVFQEEEDAGNSMTEDSNFNLNSLKVELIGEYDNHKCQVWRCRFNVTGTILSSSGDDGCVRLWKA 318

  Fly   302 NYNRQWRCAAVLKAE 316
            :|...::|.:|:..|
pombe   319 SYANLFKCISVVSLE 333

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Nup44ANP_610343.1 WD40 <8..302 CDD:441893 115/323 (36%)
WD40 repeat 16..55 CDD:293791 20/39 (51%)
WD40 repeat 60..98 CDD:293791 17/37 (46%)
WD40 repeat 118..159 CDD:293791 17/40 (43%)
WD40 repeat 166..212 CDD:293791 12/46 (26%)
WD40 repeat 221..267 CDD:293791 13/59 (22%)
WD40 repeat 275..299 CDD:293791 14/23 (61%)
seh1NP_593751.1 WD40 <13..319 CDD:441893 115/320 (36%)
WD40 repeat 64..109 CDD:293791 21/50 (42%)
WD40 repeat 114..161 CDD:293791 20/46 (43%)
WD40 repeat 172..212 CDD:293791 12/48 (25%)
WD40 repeat 218..284 CDD:293791 14/65 (22%)
WD40 repeat 292..331 CDD:293791 19/38 (50%)

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