Protein Alignment Nup44A and Sec13

DIOPT Version :10

• Sequence 1: NP_610343.1
• Gene: Nup44A / 35762
• FlyBaseID: FBgn0033247
• Length: 354
• Species: Drosophila melanogaster
• Sequence 2: NP_077168.2
• Gene: Sec13 / 110379
• MGIID: 99832
• Length: 322
• Species: Mus musculus
• Alignment Length: 332
• Identity: 103/332 - (31%)
• Similarity: 159/332 - (47%)
• Gaps: 58/332 - (17%)

  Fly    11 HKDVIHDVVFDYYGRRMATCSSDQTVKIWDEDGQGKWNVTSSWKAHSGSIWRVSWAHPEFGQVVA 75
            |:|:|||...||||.|:||||||::|||:|....|: .:.:..:.|.|.:|:|:||||.:|.::|
Mouse    12 HEDMIHDAQMDYYGTRLATCSSDRSVKIFDVRNGGQ-ILIADLRGHEGPVWQVAWAHPMYGNILA 75

  Fly    76 TCSFDRTASVWEEVIGEKVSSTNTPTRRWVRRTTLVDSRTSVTDVEFAPKYLGLLLATASADGII 140
            :||:||...:|:|..|           .|.:........:||..|.:||...||:||..|:||.|
Mouse    76 SCSYDRKVIIWKEENG-----------TWEKTHEHSGHDSSVNSVCWAPHDYGLILACGSSDGAI 129

  Fly   141 RI--YEAPDIMNLSQWPVQHEISNKLPLSC--LSWNTSTYMVTQLLAAGS--DEAATPTG----- 194
            .:  |...     .||.|: :|:|...:.|  :||       ...:..||  |:   |:|
Mouse   130 SLLTYTGE-----GQWEVK-KINNAHTIGCNAVSW-------APAVVPGSLIDQ---PSGQKPNY 178

  Fly   195 -KVFLFAYSENSRKCVKID---------TVNDITDPVTDVAFAPNAGRTFHMLAVASKD--LYIV 247
             |.|.....:|..|..:.:         .:...:|.|.|||:||:.|.....:|..|:|  ::|.
Mouse   179 IKKFASGGCDNLIKLWREEEDGQWKEEQKLEAHSDWVRDVAWAPSIGLPTSTIASCSQDGRVFIW 243

  Fly   248 NLRGVTDATDISKLDIQTIKFSEHNCPVWRVCWNMLATMLISTGDDGCVRLWRMNYNRQWRCAA- 311
            .....:......||      ..:.|..||.|.|::.|.:|..:|.|..|.||:.:.:.||.|.:
Mouse   244 TCDDASGNMWSPKL------LHKFNDVVWHVSWSITANILAVSGGDNKVTLWKESVDGQWVCISD 302

  Fly   312 VLKAEGS 318
            |.|.:||
Mouse   303 VNKGQGS 309

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nup44A	NP_610343.1	WD40	<8..302	CDD:441893	96/313 (31%)
		WD40 repeat	16..55	CDD:293791	18/38 (47%)
		WD40 repeat	60..98	CDD:293791	15/37 (41%)
		WD40 repeat	118..159	CDD:293791	15/42 (36%)
		WD40 repeat	166..212	CDD:293791	12/55 (22%)
		WD40 repeat	221..267	CDD:293791	13/47 (28%)
		WD40 repeat	275..299	CDD:293791	9/23 (39%)
Sec13	NP_077168.2	WD 1	11..50		21/38 (55%)
		WD40 repeat	17..55	CDD:293791	18/38 (47%)
		WD40	<25..289	CDD:441893	86/297 (29%)
		WD 2	55..96		18/51 (35%)
		WD40 repeat	60..98	CDD:293791	16/48 (33%)
		WD 3	101..144		17/48 (35%)
		WD40 repeat	107..147	CDD:293791	16/45 (36%)
		WD 4	148..204		12/65 (18%)
		WD40 repeat	153..207	CDD:293791	12/63 (19%)
		WD 5	210..253		12/42 (29%)
		WD40 repeat	215..259	CDD:293791	13/49 (27%)
		WD 6	260..299		14/38 (37%)
		WD40 repeat	265..289	CDD:293791	9/23 (39%)