DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CSN4 and COP8

DIOPT Version :9

Sequence 1:	NP_001163080.1	Gene:	CSN4 / 35759	FlyBaseID:	FBgn0027054	Length:	407	Species:	Drosophila melanogaster
Sequence 2:	NP_199111.1	Gene:	COP8 / 834312	AraportID:	AT5G42970	Length:	397	Species:	Arabidopsis thaliana

Alignment Length:	378	Identity:	184/378 - (48%)
Similarity:	256/378 - (67%)	Gaps:	11/378 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 GTHKDQADKYRQLLKTVLTNTGQELIDGLRLFVEAIVNEHVSLVISRQILNDVGSELSKLPDDLS 88
            |..:.:.::|:.:|.:||::  .:|:...| |::.|:::.|.||:|||:|.....||.:|..:..
plant    12 GDQRQKIEQYKLILSSVLSS--NDLLQAQR-FIDHILSDDVPLVVSRQLLQSFAQELGRLEPETQ 73

  Fly    89 KMLSHFTLEKVNPRVISFEEQVAGIRFHLANIYERNQQWRDAATVLVGIPLETGQKQYSVECKLG 153
            |.::.|||.::.|||:|||||...||..||.:||..|:|..||.:|.||.|::|.:......||.
plant    74 KEIAQFTLTQIQPRVVSFEEQALVIREKLAGLYESEQEWSKAAQMLSGIDLDSGMRAVDDNFKLS 138

  Fly   154 TYLKIARLYLEDNDSVQAELFINRASLLQAETNSEELQVLYKVCYARVLDYRRKFIEAAQRY--- 215
            ..::||||||||:|:|.||.|||:||.|.:.:.:|.|.:.|||||||:||.:|||:|||.||
plant   139 KCIQIARLYLEDDDAVNAEAFINKASFLVSNSQNEVLNLQYKVCYARILDMKRKFLEAALRYYGI 203

  Fly   216 NELSYRKI----VDQGERMTALKKALICTVLASAGQQRSRMLATLFKDERCQHLPAYGILEKMYL 276
            :::..|:|    :|:.....||..|:.||:||.||.||||:||||:|||||..|..|.||:|:||
plant   204 SQIEQRQIGDEEIDENALEQALSAAVTCTILAGAGPQRSRVLATLYKDERCSKLKIYPILQKVYL 268

  Fly   277 ERIIRRSELQEFEALLQDHQKAATSDGSSILDRAVFEHNLLSASKLYNNITFEELGALLDIPAVK 341
            |||:||.|:..|...|:.||||:..|.|::||||:.|||||||||||.||.|:|||.||.|...|
plant   269 ERILRRPEIDAFSEELRPHQKASLPDKSTVLDRAMIEHNLLSASKLYTNIRFDELGTLLAIDPRK 333

  Fly   342 AEKIASQMITEGRMNGHIDQISAIVHFENR-ELLPQWDRQIQSLCYQVNSIIE 393
            |||||:.||.:.||.|.|||..|::|||:. |.|.|||:||..||..:|.|::
plant   334 AEKIAANMIGQDRMRGSIDQEEAVIHFEDDVEELQQWDQQISGLCQALNDILD 386

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CSN4	NP_001163080.1	RPN5	<95..384	CDD:227403	159/296 (54%)
CSN4	NP_001163080.1	PCI	271..369	CDD:279707	58/97 (60%)
COP8	NP_199111.1	RPN5	<92..384	CDD:227403	155/291 (53%)
COP8	NP_199111.1	PCI	263..362	CDD:396121	59/98 (60%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	214	1.000	Domainoid score	I767
eggNOG	1	0.900	-	-		E1_KOG1497
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H8067
Inparanoid	1	1.050	343	1.000	Inparanoid score	I635
OMA	1	1.010	-	-		QHG54346
OrthoDB	1	1.010	-	-		D866823at2759
OrthoFinder	1	1.000	-	-		FOG0005728
OrthoInspector	1	1.000	-	-		oto3994
orthoMCL	1	0.900	-	-		OOG6_103354
Panther	1	1.100	-	-	LDO	PTHR10855
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X4718
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.840