Protein Alignment CSN4 and csn4

DIOPT Version :10

• Sequence 1: NP_477444.1
• Gene: CSN4 / 35759
• FlyBaseID: FBgn0027054
• Length: 407
• Species: Drosophila melanogaster
• Sequence 2: NP_593233.1
• Gene: csn4 / 2541517
• PomBaseID: SPAC22A12.03C
• Length: 377
• Species: Schizosaccharomyces pombe
• Alignment Length: 337
• Identity: 77/337 - (22%)
• Similarity: 139/337 - (41%)
• Gaps: 45/337 - (13%)

  Fly    73 LNDVGSELSKLPDDLSKMLSHFTLEKVNPRVISFE----EQVAGIRFHLANIYERNQQWRDAATV 133
            |.||...:|.|  :|.|.|    :.::...|.|.|    |.:......||.|||..|.:....:.
pombe    59 LLDVAVSISSL--ELRKEL----ISELYVPVQSLEEAPSEYLVSCCLQLATIYEAEQNFELLCSS 117

  Fly   134 LVGIPLETGQKQYSVECKLGTYLKIARLYLEDNDSVQAELFINRASLLQAETNSEELQVLYKVCY 198
            |..:. :.|..:..:|..|...:::...||:...:.:|.|.:..:..|..:.::::|.:..::|.
pombe   118 LEAVE-KHGHFENDLEQLLLLRIRLGDAYLKLGKAEKAILTVRTSIPLAFKVSNDQLLMELQLCN 181

  Fly   199 ARVLDYRRKFIEAAQRY----------NELSYRKIVDQGERMTALKKALICTVLASAGQQRSRML 253
            ||.||...:|:|||:.|          |||.||      |.:.::.:   |.:||.......:.|
pombe   182 ARALDETGQFLEAAKCYYRVLQYKVPGNELIYR------ENLCSVAQ---CLLLAIPSPIVLQFL 237

  Fly   254 ATLFKDERCQHLPAYGILEKMYLERIIRRSELQEFEALLQDHQ----KAATSDGSSILDRAVFEH 314
            ..:......:.:|.|.::||....:.|.:.:.......|..||    .....||     |...|.
pombe   238 QEISLQPSVREIPFYSLVEKYLKRKFIGKEDGAFLLPFLLPHQVIHMNRLIEDG-----RHFLET 297

  Fly   315 NLLSASKLYNNITFEELGALLDIPAVKAEKIASQMITEGRMNGHIDQISAIVHFENRELLPQWDR 379
            |:|..|:.:...:...|.....:...:.:.:.:.|:.:.|:|..|||....:.|     ||::.:
pombe   298 NILFLSEFFEVSSTSILAKHFKLSEEQVDTVVADMVIQERLNASIDQCEGYITF-----LPEYGK 357

  Fly   380 QIQSLCYQVNSI 391
             ..:|...||.|
pombe   358 -ANNLPNYVNKI 368

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CSN4	NP_477444.1	RPN5	<95..384	CDD:227403	65/306 (21%)
		PCI	271..369	CDD:460195	20/101 (20%)
		CSN4_RPN5_eIF3a	372..>403	CDD:375846	6/20 (30%)
csn4	NP_593233.1	Spy	141..>220	CDD:443119	22/84 (26%)
		PINT	283..370	CDD:214509	21/97 (22%)