DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CSN4 and csn4

DIOPT Version :9

Sequence 1:	NP_001163080.1	Gene:	CSN4 / 35759	FlyBaseID:	FBgn0027054	Length:	407	Species:	Drosophila melanogaster
Sequence 2:	NP_593233.1	Gene:	csn4 / 2541517	PomBaseID:	SPAC22A12.03c	Length:	377	Species:	Schizosaccharomyces pombe

Alignment Length:	337	Identity:	77/337 - (22%)
Similarity:	139/337 - (41%)	Gaps:	45/337 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    73 LNDVGSELSKLPDDLSKMLSHFTLEKVNPRVISFE----EQVAGIRFHLANIYERNQQWRDAATV 133
            |.||...:|.|  :|.|.|    :.::...|.|.|    |.:......||.|||..|.:....:.
pombe    59 LLDVAVSISSL--ELRKEL----ISELYVPVQSLEEAPSEYLVSCCLQLATIYEAEQNFELLCSS 117

  Fly   134 LVGIPLETGQKQYSVECKLGTYLKIARLYLEDNDSVQAELFINRASLLQAETNSEELQVLYKVCY 198
            |..:. :.|..:..:|..|...:::...||:...:.:|.|.:..:..|..:.::::|.:..::|.
pombe   118 LEAVE-KHGHFENDLEQLLLLRIRLGDAYLKLGKAEKAILTVRTSIPLAFKVSNDQLLMELQLCN 181

  Fly   199 ARVLDYRRKFIEAAQRY----------NELSYRKIVDQGERMTALKKALICTVLASAGQQRSRML 253
            ||.||...:|:|||:.|          |||.||      |.:.::.:   |.:||.......:.|
pombe   182 ARALDETGQFLEAAKCYYRVLQYKVPGNELIYR------ENLCSVAQ---CLLLAIPSPIVLQFL 237

  Fly   254 ATLFKDERCQHLPAYGILEKMYLERIIRRSELQEFEALLQDHQ----KAATSDGSSILDRAVFEH 314
            ..:......:.:|.|.::||....:.|.:.:.......|..||    .....||     |...|.
pombe   238 QEISLQPSVREIPFYSLVEKYLKRKFIGKEDGAFLLPFLLPHQVIHMNRLIEDG-----RHFLET 297

  Fly   315 NLLSASKLYNNITFEELGALLDIPAVKAEKIASQMITEGRMNGHIDQISAIVHFENRELLPQWDR 379
            |:|..|:.:...:...|.....:...:.:.:.:.|:.:.|:|..|||....:.|     ||::.:
pombe   298 NILFLSEFFEVSSTSILAKHFKLSEEQVDTVVADMVIQERLNASIDQCEGYITF-----LPEYGK 357

  Fly   380 QIQSLCYQVNSI 391
             ..:|...||.|
pombe   358 -ANNLPNYVNKI 368

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CSN4	NP_001163080.1	RPN5	<95..384	CDD:227403	65/306 (21%)
CSN4	NP_001163080.1	PCI	271..369	CDD:279707	20/101 (20%)
csn4	NP_593233.1	PAM	283..370	CDD:214803	21/97 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1497
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54346
OrthoFinder	1	1.000	-	-		FOG0005728
OrthoInspector	1	1.000	-	-		oto100896
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR10855
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2466
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.950