DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG8726 and SNX21

DIOPT Version :9

Sequence 1:	NP_610341.2	Gene:	CG8726 / 35758	FlyBaseID:	FBgn0033244	Length:	646	Species:	Drosophila melanogaster
Sequence 2:	NP_219489.1	Gene:	SNX21 / 90203	HGNCID:	16154	Length:	373	Species:	Homo sapiens

Alignment Length:	147	Identity:	40/147 - (27%)
Similarity:	66/147 - (44%)	Gaps:	12/147 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 QALSCEITAVQEVAG-HTEYLLR----VWRGASNKNYWTVLRRYNDFDRLDKSL----RVSGIEL 73
            |.|..|:|:...|.. .::|:|.    :..|..:.....:.|||:||:||.::|    |.....:
Human   129 QRLLFEVTSANVVKDPPSKYVLYTLAVIGPGPPDCQPAQISRRYSDFERLHRNLQRQFRGPMAAI 193

  Fly    74 PLPRKRIFGNMRPEFIAERKQALQEYINAVLMNPILASSLPAKR-FVDPE-SYSQSFHDHAVQNA 136
            ..||||:..|...|.||.|.:|.::::..:...|.|..:...:. ||.|| ..:||.....:...
Human   194 SFPRKRLRRNFTAETIARRSRAFEQFLGHLQAVPELRHAPDLQDFFVLPELRRAQSLTCTGLYRE 258

  Fly   137 MLCLRNDTTWSLGGSMG 153
            .|.|..: .|.|...:|
Human   259 ALALWAN-AWQLQAQLG 274

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8726	NP_610341.2	PX_MONaKA	13..132	CDD:132781	35/124 (28%)
CG8726	NP_610341.2	PKc	237..432	CDD:270622
SNX21	NP_219489.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..107
		PX_SNX21	131..242	CDD:132834	30/110 (27%)
		TPR repeat	244..268	CDD:276809	4/24 (17%)
		TPR_12	247..312	CDD:290160	7/29 (24%)
		TPR repeat	281..312	CDD:276809
		TPR repeat	326..353	CDD:276809
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2101
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900