Protein Alignment CG8726 and snz

DIOPT Version :10

• Sequence 1: NP_610341.2
• Gene: CG8726 / 35758
• FlyBaseID: FBgn0033244
• Length: 646
• Species: Drosophila melanogaster
• Sequence 2: NP_572421.1
• Gene: snz / 31704
• FlyBaseID: FBgn0029976
• Length: 1117
• Species: Drosophila melanogaster
• Alignment Length: 615
• Identity: 119/615 - (19%)
• Similarity: 188/615 - (30%)
• Gaps: 250/615 - (40%)

  Fly    31 AGHTEYLLRVWRGASNKNYWTVLRRYNDFDRLDKSLR-----VSGIELPLPRKRIFGNMRPEFIA 90
            :||..  ||. |.:...:.|.|:|..|....|.:.||     :..|:||...|..|.........
  Fly   695 SGHAN--LRK-RPSGISSGWVVMRSLNQVHELQRKLRHVSSNLKAIDLPTNFKFFFLKTDRHGQE 756

  Fly    91 ERKQALQEYINAVLMNPILASSLPAKRFVDPESYSQSFHDHAVQNAMLCLRNDTTWSLGGSMGAI 155
            :.|..:|:::|.:|.:..|..|.....|:.|.|      ||
  Fly   757 KAKSQIQKFLNFILEDDHLNGSEAIYTFLSPSS------DH------------------------ 791

  Fly   156 GWRLRKHYFKVTTKPPEKS--SNKQLVKSGSQTHQSKHFAAGSSNGSGHSIDAGTLDP------G 212
                    .|.:...|:||  |...|.:|.:              |..|.....| ||      .
  Fly   792 --------LKQSLPSPKKSKFSLSTLFRSDA--------------GKAHEASKAT-DPFWGLQRD 833

  Fly   213 SEVVAEWLEYGPDKFIDEKEIGGIMKSLMGLQHPHIEPVLLAAHTENGCLVIRKFHKHGTLKDVL 277
            .|.::.:|         :.|.||             |..:|||..::              ||.:
  Fly   834 DEDISTYL---------DGESGG-------------EAKMLAADLDS--------------KDSI 862

  Fly   278 CMAANPKNTFLSKYGNPKG------RTALSMKQVATYG----KQILEALIFLHSKGYAYGHLHSG 332
               |.|....:.:..:..|      ::.:|..|: |||    :||.|::.:|..:.
  Fly   863 ---AEPMYALMGEIFDMGGVFKWLRKSLISFVQI-TYGRTINRQIRESVAYLFEES--------- 914

  Fly   333 NIVIVDDCVKLLDIENFLLGVPAFYRPFFMQHSKIHAIETIDVYCFGHVLFEMAMGYPLQESVVR 397
                                         |.|:...||  :..:..|.||   |..||.:...:|
  Fly   915 -----------------------------MLHNYFSAI--LKSFWPGGVL---ASAYPTRSEDMR 945

  Fly   398 QITECPEALKCLLESILSKEACKAGLPTLEQLLGHRFFLQYASTESAGAAANAEKPYFKLSLNAK 462
            ::|  ..|.|.||...:.:..|        .|:|            |.||
  Fly   946 EMT--TTAAKALLTDHIPEVLC--------NLVG------------AQAA--------------- 973

  Fly   463 ELLKQAAIKSENRLRDEQKSVKNQKRIVRVQELMSSE--EEKRKSKQKAKLEHKQSKLKQQSSIQ 525
               |:..:|..:.|   |....|::....:.|::..|  .|.|                 |..:.
  Fly   974 ---KRGVLKVFDAL---QNPAYNKQLFYELLEILMIEFFPEIR-----------------QLRVS 1015

  Fly   526 TNNG-RLSLVAATAAAASSSTTVVGELCGTDSFNRSDSTPEEPTTLAGIKSPPLTPGPHLGSIYQ 589
            .:|| :|:...|.|||||::..:|.                 .|..|.:.|...:.|.|..
  Fly  1016 NSNGTKLNTATAGAAAASAAAALVA-----------------ATASASLPSLNHSGGGHSA---- 1059

  Fly   590 QELPSTTGAPVERQSSTPNMLSEDAEGGDG 619
                ||.|....:.||:.:..|..|.|..|
  Fly  1060 ----STGGHQNHQGSSSASGSSAGASGATG 1085

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8726	NP_610341.2	PX_MONaKA	13..132	CDD:132781	27/105 (26%)
		Protein Kinases, catalytic domain	237..432	CDD:473864	36/204 (18%)
		WH2	622..646	CDD:425359
snz	NP_572421.1	PXA	142..300	CDD:460484
		RGS_SNX25	422..531	CDD:188675
		PX_SNX25	645..788	CDD:132788	24/95 (25%)
		Nexin_C	882..987	CDD:462541	35/191 (18%)