DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8726 and SNX15

DIOPT Version :9

Sequence 1:	NP_610341.2	Gene:	CG8726 / 35758	FlyBaseID:	FBgn0033244	Length:	646	Species:	Drosophila melanogaster
Sequence 2:	NP_037438.2	Gene:	SNX15 / 29907	HGNCID:	14978	Length:	342	Species:	Homo sapiens

Alignment Length:	116	Identity:	27/116 - (23%)
Similarity:	45/116 - (38%)	Gaps:	18/116 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 GHTEYLLRVW----RGASNKNYWTVLRRYNDFDRLDKSLRVSGIEL--------PLPRKRIFGNM 84
            |:|||.:...    :...:.....|.:||:||.:|...|..:...|        ..||.::||..
Human    24 GYTEYKVTAQFISKKDPEDVKEVVVWKRYSDFRKLHGDLAYTHRNLFRRLEEFPAFPRAQVFGRF 88

  Fly    85 RPEFIAERKQALQEYINAVLMNPILASSLPAKRF------VDPESYSQSFH 129
            ....|.||::..::.:...:..|.|.:|...|.|      ..|...|:..|
Human    89 EASVIEERRKGAEDLLRFTVHIPALNNSPQLKEFFRGGEVTRPLEVSRDLH 139

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8726	NP_610341.2	PX_MONaKA	13..132	CDD:132781	27/116 (23%)
CG8726	NP_610341.2	PKc	237..432	CDD:270622
SNX15	NP_037438.2	PX_domain	9..126	CDD:321991	24/101 (24%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	245..267
		MIT_SNX15	267..341	CDD:239140
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2101
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900