DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8726 and Rps6kc1

DIOPT Version :9

Sequence 1:	NP_610341.2	Gene:	CG8726 / 35758	FlyBaseID:	FBgn0033244	Length:	646	Species:	Drosophila melanogaster
Sequence 2:	XP_006250521.1	Gene:	Rps6kc1 / 289342	RGDID:	1306578	Length:	1045	Species:	Rattus norvegicus

Alignment Length:	442	Identity:	91/442 - (20%)
Similarity:	141/442 - (31%)	Gaps:	167/442 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly    89 IAERKQALQEYINAVLMNPILASSLPAK-------RFVDPESYSQSFHDHAVQNAMLCLR----- 141
            |:.::.|.::..:|....|.|..:||.:       ..|||..:||:.........:||||
  Rat   666 ISFKEAASEDVCSAEEGRPDLLVNLPGELQPTKETSAVDPTKFSQASIGRLEAPDVLCLRLSSEQ 730

  Fly   142 -------------NDTTWSLGG---------SMGAIGWRLRKHYFKVTTKPPEKSSNKQLVKS-- 182
                         :.|.:..||         .:|.:          .|......||..|.:.|
  Rat   731 CHDLGQEGPEELSHPTEFRPGGVTPERSAQADLGVL----------FTATVDHSSSQDQFLFSSL 785

  Fly   183 -----------GSQTHQSK-----HFA---AGSSNGSGHSIDAGTLDPGSEVVAEWLEYGPDKFI 228
                       |:.|.|..     |.|   :|:...|.|: |..|    ||.|..:.|  |.|..
  Rat   786 HSESDRLGQVEGAVTSQDLQESLFHIASPCSGAKEDSAHT-DTAT----SEEVLLFTE--PSKEG 843

  Fly   229 D-------------EKEIGGIMKSLMGLQHPHIEPVLLAAH--TENGCL---------VIRKFHK 269
            |             |||:..|.:.|       .:.:.::|.  ...||:         .:...|:
  Rat   844 DSEAKVRSVGAGGAEKEVHQIFEDL-------DQRLAVSARLFIPEGCIQRWAAEMVVALDALHR 901

  Fly   270 HGTLKDVLCMAANPKNTFLSKYGNPKGRTALSMKQVATYGKQILEALIFLHSKGYAYGHLHSGNI 334
            .|    ::|...||.|..|    |..|...|      ||..:..|
  Rat   902 EG----IVCRDLNPNNILL----NDGGHIQL------TYFSRWSE-------------------- 932

  Fly   335 VIVDDCVKLLDIENFLLGVPAFYRPFFMQHSKIHAI----ETIDVYCFGHVLFEMAMGYPLQE-- 393
              |:|   |.|.:       |..|.:..  .::.|:    |..|.:..|.||||:..|..|.|
  Rat   933 --VED---LCDSD-------AIARMYCA--PEVGAVTEETEACDWWSLGAVLFELLTGKTLVECH 983

  Fly   394 ------SVVRQITEC-PEALKCLLESILS---KEACKAGLPTLEQLLGHRFF 435
                  .....:.:| .|..:.|::.:|.   .|...||:..:|.:..|.||
  Rat   984 PAGINTHTTLNMPDCVSEEARSLIQQLLQFNPMERLGAGVAGVEDIKSHPFF 1035

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8726	NP_610341.2	PX_MONaKA	13..132	CDD:132781	12/49 (24%)
CG8726	NP_610341.2	PKc	237..432	CDD:270622	42/221 (19%)
Rps6kc1	XP_006250521.1	PX_RPK118_like	11..128	CDD:132820
		MIT_SNX15	237..305	CDD:239140
		PKc_like	334..>420	CDD:304357
		STKc_RPK118_like	<858..1035	CDD:270728	47/231 (20%)
		S_TKc	<867..1035	CDD:214567	43/222 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2101
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900