DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8726 and SNX13

DIOPT Version :9

Sequence 1:	NP_610341.2	Gene:	CG8726 / 35758	FlyBaseID:	FBgn0033244	Length:	646	Species:	Drosophila melanogaster
Sequence 2:	NP_001337791.1	Gene:	SNX13 / 23161	HGNCID:	21335	Length:	968	Species:	Homo sapiens

Alignment Length:	203	Identity:	51/203 - (25%)
Similarity:	86/203 - (42%)	Gaps:	39/203 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 IDDTQALSCEITAVQEVA---GHTEYLLRVW---RGASNKNYWTVLRRYNDFD----RLDKSLRV 68
            |.||.....:..||..|.   |.|..|..:.   |..:::..|...|||:||.    |:.:....
Human   565 ISDTVYADYDPYAVAGVCNDHGKTYALYAITVHRRNLNSEEMWKTYRRYSDFHDFHMRITEQFES 629

  Fly    69 SGIELPLPRKRIFGNMRPEFIAERKQALQEYINAVLMNPILASSLPAKR-----FVDPESYSQSF 128
            ....|.||.|:.|.||..:|:.:||:.|..|:. :|:.|.:..:.||..     |::.::||:..
Human   630 LSSILKLPGKKTFNNMDRDFLEKRKKDLNAYLQ-LLLAPEMMKASPALAHYVYDFLENKAYSKGK 693

  Fly   129 HDHA----------------VQNAMLCLRN---DTTWSLGGSMGAIGWRL----RKHYFKVTTKP 170
            .|.|                |.||:..|.:   :....:..:||.:..||    ::.:|||....
Human   694 GDFARKMDTFVNPLRNSMRNVSNAVKSLPDSLAEGMTKMSDNMGKMSERLGQDIKQSFFKVPPLI 758

  Fly   171 PEKSSNKQ 178
            |:..|:.:
Human   759 PKTDSDPE 766

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8726	NP_610341.2	PX_MONaKA	13..132	CDD:132781	37/132 (28%)
CG8726	NP_610341.2	PKc	237..432	CDD:270622
SNX13	NP_001337791.1	PXA	97..284	CDD:214611
		RGS_SNX13	377..511	CDD:188674
		PX_SNX13	557..687	CDD:132783	34/122 (28%)
		Nexin_C	803..911	CDD:312222
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2101
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900