DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8726 and Snx13

DIOPT Version :9

Sequence 1:	NP_610341.2	Gene:	CG8726 / 35758	FlyBaseID:	FBgn0033244	Length:	646	Species:	Drosophila melanogaster
Sequence 2:	XP_006515125.3	Gene:	Snx13 / 217463	MGIID:	2661416	Length:	1144	Species:	Mus musculus

Alignment Length:	199	Identity:	54/199 - (27%)
Similarity:	84/199 - (42%)	Gaps:	48/199 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 IDDTQALSCEITAVQEVA---GHTEYLLRVW---RGASNKNYWTVLRRYNDFDRLDKSLRV---- 68
            |.||.....:..||..|.   |.|..|..:.   |..:.:..|...|||:||.  |..:|:
Mouse   741 ISDTVYADYDPYAVAGVCNDHGKTYALYAITVHRRNLNTEEMWKTYRRYSDFH--DFHMRITEQF 803

  Fly    69 ---SGIELPLPRKRIFGNMRPEFIAERKQALQEYINAVLMNPILASSLPAKR-----FVDPESYS 125
               |.| |.||.|:.|.||..:|:.:||:.|..|:. :|:.|.:..:.||..     |::.::||
Mouse   804 ENLSSI-LKLPGKKTFNNMDRDFLEKRKKDLNAYLQ-LLLTPEMMKASPALAHCVYDFLENKAYS 866

  Fly   126 QSFHDHA----------------VQNAMLCLRND-----TTWS--LGGSMGAIGWRLRKHYFKVT 167
            :...|.|                |.||:..|.:.     |..|  :|.....:|..:::.:|||
Mouse   867 KGKGDFARKMDTFVNPLRNSMRNVSNAVKSLPDSLAEGVTKMSDNVGRMSERLGQDIKQSFFKV- 930

  Fly   168 TKPP 171
              ||
Mouse   931 --PP 932

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8726	NP_610341.2	PX_MONaKA	13..132	CDD:132781	40/135 (30%)
CG8726	NP_610341.2	PKc	237..432	CDD:270622
Snx13	XP_006515125.3	PHA03381	6..>146	CDD:177618
		PXA	273..460	CDD:214611
		RGS_SNX13	553..687	CDD:188674
		PX_SNX13	733..863	CDD:132783	37/125 (30%)
		Nexin_C	979..1087	CDD:370015
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2101
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900