Protein Alignment CG8726 and Sgk3

DIOPT Version :9

• Sequence 1: NP_610341.2
• Gene: CG8726 / 35758
• FlyBaseID: FBgn0033244
• Length: 646
• Species: Drosophila melanogaster
• Sequence 2: NP_001032848.1
• Gene: Sgk3 / 170755
• MGIID: 2182368
• Length: 496
• Species: Mus musculus
• Alignment Length: 486
• Identity: 109/486 - (22%)
• Similarity: 166/486 - (34%)
• Gaps: 135/486 - (27%)

  Fly    21 SCEITAVQEVAGHTE-------YLLRVWRGASNKNYWTVLRRYNDFDRLDKSLR--VSGIELPLP 76
            ||...::.....|.|       |.:.|..|.|.   |.|.|||.:||:|..||:  ...:.|.:|
Mouse    12 SCPSVSIPSSDEHREKKKRFTVYKVLVSVGRSE---WFVFRRYAEFDKLYNSLKKQFPAMALKIP 73

  Fly    77 RKRIFG-NMRPEFIAERKQALQEYINAVLMNPILASSLPAKRFV---DPESYSQSFHDHAVQNAM 137
            .||||| |..|:||.:|:..|.|:|..::..|.|.:....:.|:   .|...|....|...::
Mouse    74 AKRIFGDNFDPDFIKQRRAGLNEFIQNLVRYPELYNHPDVRAFLQMDSPRHQSDPSEDEDERS-- 136

  Fly   138 LCLRNDTTWSLGGSMGAIGWRLRKHYFKVTTKPPEKSSNKQLVKSGSQTHQSKHFAAGSSNGSGH 202
                                         |:||...|.|..|..:|:...:...|......|.|.
Mouse   137 -----------------------------TSKPHSTSRNINLGPTGNPHAKPTDFDFLKVIGKGS 172

  Fly   203 SIDAGTLDPGSEVVAEWLEYGPDKF-----------IDEKEIGGIMKS----LMGLQHPHIEPVL 252
            .        |..::|:....|  ||           ::.||...||..    |..::||.:..:.
Mouse   173 F--------GKVLLAKRKLDG--KFYAVKVLQKKIVLNRKEQKHIMAERNVLLKNVKHPFLVGLH 227

  Fly   253 LAAHTENGCLVIRKFHKHGTLKDVLCMAANPKNTFL-----SKYGNPKGRTALSMKQVATYGKQI 312
            .:..|......:..|...|.|             |.     ..:..|:.|         .|..:|
Mouse   228 YSFQTTEKLYFVLDFVNGGEL-------------FFHLQRERSFPEPRAR---------FYAAEI 270

  Fly   313 LEALIFLHSKGYAYGHL--------HSGNIVIVD-----DCVKLLDIENFLLGVPAFYRPFFMQH 364
            ..||.:|||....|..|        ..|::|:.|     :.:.:.|......|.|.:..|..::.
Mouse   271 ASALGYLHSIKIVYRDLKPENILLDSMGHVVLTDFGLCKEGIAISDTTTTFCGTPEYLAPEVIRK 335

  Fly   365 SKIHAIETIDVYCFGHVLFEMAMGYPLQESVVRQITEC-------PEALK--------CLLESIL 414
            ....  .|:|.:|.|.||:||..|.|  ....|.:.|.       |..|:        .:||.:|
Mouse   336 QPYD--NTVDWWCLGAVLYEMLYGLP--PFYCRDVAEMYDNILHKPLNLRPGVSLTAWSILEELL 396

  Fly   415 SKEACKAGLPTLEQLL---GHRFFLQYASTE 442
            .|.. :..|...|..|   .|.||...:.|:
Mouse   397 EKNR-QNRLGAKEDFLEIQNHPFFESLSWTD 426

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8726	NP_610341.2	PX_MONaKA	13..132	CDD:132781	39/123 (32%)
		PKc	237..432	CDD:270622	48/234 (21%)
Sgk3	NP_001032848.1	PX_CISK	12..120	CDD:132780	36/110 (33%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	121..157		10/66 (15%)
		S_TKc	162..419	CDD:214567	60/293 (20%)
		STKc_SGK3	165..490	CDD:270755	62/299 (21%)
		Nuclear localization signal. /evidence=ECO:0000250	195..205		2/9 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2101
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810