Protein Alignment CG8726 and snz

DIOPT Version :10

• Sequence 1: NP_610341.2
• Gene: CG8726 / 35758
• FlyBaseID: FBgn0033244
• Length: 646
• Species: Drosophila melanogaster
• Sequence 2: XP_061505781.1
• Gene: snz / 1277426
• VectorBaseID: AGAMI1_014933
• Length: 1161
• Species: Anopheles gambiae
• Alignment Length: 595
• Identity: 122/595 - (20%)
• Similarity: 188/595 - (31%)
• Gaps: 224/595 - (37%)

  Fly    50 WTVLRRYNDFDRLDKSLRVSGIE---LPLPRKRIF-----GNMRPEFIAERKQALQEYINAVLMN 106
            |.|:|....|..|.:.||...:|   |.||....|     .|.| ..:.:.|..:|.|::.:|.:
Mosquito   743 WVVVRSLTQFHALHRKLRPMCVELRQLDLPSNNAFKLFLLKNDR-ALLEKAKAQVQRYLSFILED 806

  Fly   107 PILASSLPAKRFVDPESYSQSFHDHAVQNAMLCLRNDTTWSLGGSMGAIGWRLRKHYFKVTTKPP 171
            ..|..|.....|:.|.|.                                 ||::........|.
Mosquito   807 DHLNQSEAVYEFLSPSSD---------------------------------RLKQGVLTGNPSPS 838

  Fly   172 EKSSNK---------------QL--VKSGSQTHQSKHFAAGSSNGSGHSIDAGTLDPGSEVVAEW 219
            :|.::|               ||  |.||......:.|.:|...|:.|..|....|  ::.|:.:
Mosquito   839 KKQTSKFSLATIFRSNSDKLEQLWHVGSGGGAGGERPFGSGGGGGTDHHPDFTPED--ADQVSLY 901

  Fly   220 LEYGPDKFIDEKEIGGIMKSLMGLQHPHIEPVLLAAHTENGCLVIRKFHKHGTLKDVLCMAANPK 284
            ||.||..       .|  .|..|...|          |:...:.:.       |:|.:   |.|.
Mosquito   902 LEGGPAP-------SG--PSSSGASPP----------TDGAAVAME-------LRDSI---AEPL 937

  Fly   285 NTFLSKYGNPKG------RTALSMKQVATYG----KQILEALIFLHSK----GYAYGHLHS---G 332
            ...|.:..:..|      ::.:|..|: |||    :|:.|::..|..:    .||...|.|   |
Mosquito   938 YGLLGEIFDLGGVFRWLRKSLISFVQI-TYGQTINRQLRESIAALFDEPMLHAYASAVLRSLWPG 1001

  Fly   333 NIVIVDDCVKLLDIENFLLGVPAFYRPFFMQHSKIHAIETIDVYCFGHVLFEMAMGYPLQESVVR 397
            ...:..|.|:||         |:             |..|.|..       ||.|
Mosquito  1002 GGTLQADGVRLL---------PS-------------AERTEDER-------EMIM---------- 1027

  Fly   398 QITECPEALKCLLESILSKEACKAGLPTLEQLLGHRFFLQYASTESAGAAANAEKPYFKLSLNAK 462
                  .|.:.||:..:.:..|        .|:|               |.||
Mosquito  1028 ------NAARSLLQDNIPELLC--------SLIG---------------AQNA------------ 1051

  Fly   463 ELLKQAAIKSENRLRDEQKSVKNQKRIVRVQELMSSE--EEKRKSKQKAKLEHKQSKLKQQSSIQ 525
               :|.|:|....|   |.|:.|::....:.|.:..|  .|.|:.|..|               .
Mosquito  1052 ---RQGALKLFEVL---QNSLYNKQLFYDLLETLMLELFPEIRQLKPAA---------------A 1095

  Fly   526 TNNGRLSLVAATAAAASSSTTVVGELCGTDSFNRSDSTPEEPTTLAGIKSPPLTPGPHLGSIYQQ 590
            .:.|..:.||...|..|||::.|  |...:..::..:....|.  |.|.||| ||...:|
Mosquito  1096 GSTGNCATVAPGHATGSSSSSTV--LRPREYHHQPAAAGSSPA--APIYSPP-TPTGAVG----- 1150

  Fly   591 ELPSTTGAPV 600
               |.:|.|:
Mosquito  1151 ---SASGTPI 1157

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8726	NP_610341.2	PX_MONaKA	13..132	CDD:132781	23/89 (26%)
		Protein Kinases, catalytic domain	237..432	CDD:473864	39/211 (18%)
		WH2	622..646	CDD:425359
snz	XP_061505781.1	None