DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14763 and DYNLT2B

DIOPT Version :9

Sequence 1:	NP_001286175.1	Gene:	CG14763 / 35757	FlyBaseID:	FBgn0033243	Length:	189	Species:	Drosophila melanogaster
Sequence 2:	NP_001338557.1	Gene:	DYNLT2B / 255758	HGNCID:	28482	Length:	148	Species:	Homo sapiens

Alignment Length:	142	Identity:	37/142 - (26%)
Similarity:	72/142 - (50%)	Gaps:	18/142 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    56 MGVSLPM--GAPAAKP-------TMRFMPTYRLESKNPLNKERVENIIK-AVMNRHYNDEYMFHP 110
            :|||..:  |.|.|:.       |....|.::...:..:.|:.:..::| .:.|..|:.|.|  |
Human     5 IGVSFSVGDGVPEAEKNAGEPENTYILRPVFQQRFRPSVVKDCIHAVLKEELANAEYSPEEM--P 67

  Fly   111 KHSLHMAAQVSEEIKNRIKLDNYDRYRYIVLVTVGEFLMQGLYSMVNFLWDAEKDGFVTYSVERP 175
            :.:.|:    ||.||:::|...:|||:.:|.|.:||...:|::......|||:.|.: |:.|..
Human    68 QLTKHL----SENIKDKLKEMGFDRYKMVVQVVIGEQRGEGVFMASRCFWDADTDNY-THDVFM- 126

  Fly   176 SYFAVCTTFYLY 187
            ::...|::.:|:
Human   127 NFILRCSSIWLF 138

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14763	NP_001286175.1	DLC-like_SF	86..186	CDD:425407	28/100 (28%)
DYNLT2B	NP_001338557.1	Tctex-1	44..127	CDD:308957	27/90 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165148552
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4108
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR21255
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.840