Protein Alignment nito and SRSF9

DIOPT Version :9

• Sequence 1: NP_001286174.1
• Gene: nito / 35756
• FlyBaseID: FBgn0027548
• Length: 793
• Species: Drosophila melanogaster
• Sequence 2: NP_003760.1
• Gene: SRSF9 / 8683
• HGNCID: 10791
• Length: 221
• Species: Homo sapiens
• Alignment Length: 264
• Identity: 61/264 - (23%)
• Similarity: 88/264 - (33%)
• Gaps: 106/264 - (40%)

  Fly   316 LFAGNLEVTIADDELRRIFGKYGVVDDIDIKR-----PPPGTGNAFAFVRYQNLDMAHRAKIELS 375
            ::.|||...:.:.:|..:|.|||.:.:|::|.     |       |||||:::...|..|....:
Human    16 IYVGNLPTDVREKDLEDLFYKYGRIREIELKNRHGLVP-------FAFVRFEDPRDAEDAIYGRN 73

  Fly   376 GQYIGKFQCKIGYGKVTPATRMWIGGLGAWTSVTQLEREFDRFGAIKKIEYQKGEPYAYIQYETV 440
            |...|:.:.::.:    |.|   .||.|.|.
Human    74 GYDYGQCRLRVEF----PRT---YGGRGGWP---------------------------------- 97

  Fly   441 EAATAAVKEMRGFPLGGPERRLRTDFAEL-PGATPAAPFKSSKPPYDESA--------------L 490
                      ||...|.|.|  |:||..| .|..|:..::..|....|:.              :
Human    98 ----------RGGRNGPPTR--RSDFRVLVSGLPPSGSWQDLKDHMREAGDVCYADVQKDGVGMV 150

  Fly   491 EYRRPEYDPY------------YEESAAYAPRGGYSPYPPRG---GY-RGRGGYRGR-----GRG 534
            ||.|.|...|            :|...:|     ...||.|.   || |.|.|.|||     .||
Human   151 EYLRKEDMEYALRKLDDTKFRSHEGETSY-----IRVYPERSTSYGYSRSRSGSRGRDSPYQSRG 210

  Fly   535 MYHY 538
            ..||
Human   211 SPHY 214

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nito	NP_001286174.1	RRM	<56..>223	CDD:223796
		RRM1_Spen	98..175	CDD:240754
		RRM2_Spen	312..390	CDD:240755	20/78 (26%)
		RRM3_Spen	397..467	CDD:240756	11/69 (16%)
		SPOC	630..789	CDD:311609
SRSF9	NP_003760.1	RRM1_SRSF9	15..86	CDD:241042	20/76 (26%)
		RRM2_SRSF9	104..186	CDD:410161	19/88 (22%)
		Interaction with SAFB1	188..200		5/11 (45%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	189..221		12/26 (46%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910