DRSC/TRiP Functional Genomics Resources

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Protein Alignment nito and SRSF4

DIOPT Version :9

Sequence 1:NP_001286174.1 Gene:nito / 35756 FlyBaseID:FBgn0027548 Length:793 Species:Drosophila melanogaster
Sequence 2:NP_005617.2 Gene:SRSF4 / 6429 HGNCID:10786 Length:494 Species:Homo sapiens


Alignment Length:345 Identity:78/345 - (22%)
Similarity:124/345 - (35%) Gaps:103/345 - (29%)


- Green bases have known domain annotations that are detailed below.


  Fly   316 LFAGNLEVTIADDELRRIFGKYGVVDDIDIKRPPPGTGNAFAFVRYQNLDMAHRAKIELSGQYI- 379
            ::.|.|.....:.::.|.|..||.:.::|:|       |.:.||.:.:|..|..|..||:|:.: 
Human     4 VYIGRLSYQARERDVERFFKGYGKILEVDLK-------NGYGFVEFDDLRDADDAVYELNGKDLC 61

  Fly   380 ---------------GKF-QCKIGYG-------KVTPAT----RMWIGGLGAWTSVTQLEREFDR 417
                           |.: ..:.|||       |..|.|    |:.:..|.:..|...|:....:
Human    62 GERVIVEHARGPRRDGSYGSGRSGYGYRRSGRDK
YGPPTRTEYRLIVENLSSRCSWQDLKDYMRQ 126

  Fly   418 FGAIKKIEYQKG-EPYAYIQYETVEAATAAVKEMRGFPLGGPERRLRTDFAELPGATPAAPFKSS 481
            .|.:...:..|| :....|::.:......|::::.|..:.|.:.||..|   .||:         
Human   127 AGEVTYADAHKGRKNEGVIEFVSYSDMKRALEKLDGTEVNGRKIRLVED---KPGS--------- 179

  Fly   482 KPPYDESALEYRRPEYDPYYEESAAYAPRGGYSPYPPRGGYRGRGGYRGRGRGMYHYHNDVHRPP 546
                       ||               |..||        |.|...|.|.|..   |:...|  
Human   180 -----------RR---------------RRSYS--------RSRSHSRSRSRSR---HSRKSR-- 205

  Fly   547 HPGSLAGSSSSVPPPGGVEDEWRRPPGESYDR-GARSSSREPGVERSRSRSPLKRARSPGSDSDT 610
               |.:|||.|           ......|..| |:||.|:.....:|||||..:::|||..:...
Human   206 ---SRSGSSKS-----------SHSKSRSRSRSGSRSRSKSRSRSQSRSRSKKEKSRSPSKEKSR 256

  Fly   611 STRRNDALASASTVPDVARK 630
            | |.:.|..|.|...|.|.:
Human   257 S-RSHSAGKSRSKSKDQAEE 275

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
nitoNP_001286174.1 RRM <56..>223 CDD:223796
RRM1_Spen 98..175 CDD:240754
RRM2_Spen 312..390 CDD:240755 21/97 (22%)
RRM3_Spen 397..467 CDD:240756 13/70 (19%)
SPOC 630..789 CDD:311609 0/1 (0%)
SRSF4NP_005617.2 RRM1_SRSF4_like 3..72 CDD:240783 17/74 (23%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 72..95 4/22 (18%)
RRM2_SRSF4_like 104..175 CDD:241044 13/70 (19%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 169..494 43/173 (25%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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