DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment nito and rbm4.3

DIOPT Version :9

Sequence 1:	NP_001286174.1	Gene:	nito / 35756	FlyBaseID:	FBgn0027548	Length:	793	Species:	Drosophila melanogaster
Sequence 2:	XP_005172323.1	Gene:	rbm4.3 / 406277	ZFINID:	ZDB-GENE-040426-1938	Length:	362	Species:	Danio rerio

Alignment Length:	384	Identity:	89/384 - (23%)
Similarity:	129/384 - (33%)	Gaps:	110/384 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   281 PRPHAPYEK-----PESKKDKFPNYLHHVQPEDDPLSTRTLFAGNLEVTIADDELRRIFGKYGVV 340
            |.||...||     ..:|..|                   :|.|||......|||:.:|.:||.|
Zfish     4 PLPHCGEEKAAWHNTSAKMVK-------------------IFIGNLPQQAEVDELKSLFSQYGTV 49

  Fly   341 DDIDIKRPPPGTGNAFAFVRYQNLDMAHRA--KIELSGQYIGKFQCKIGYGKVTPATRMWIGGLG 403
            .:..|.:       .||||...:...|.:|  .:.|...:......:...||.....::.:..:.
Zfish    50 TECAIIK-------NFAFVHMDDRKSATKAIKNLHLYKLHGTPINVEASRGKNQGPVKLHVANVE 107

  Fly   404 AWTSVTQLEREFDRFGAIKKIEYQKGEPYAYIQYETVEAATAAVKEMRGFPLGGPERRLRTDFAE 468
            ..|. .:|...|:.:|.:.:....|.  :|::.....:.|..|:|.:              |..|
Zfish   108 KGTD-DELRALFEDYGTVAECAIIKN--FAFVHMNNSDEAMDAIKGL--------------DNTE 155

  Fly   469 LPGATPAAPFKSSKPPYDESALEYRRPE---YDPYY----EESAAYAPRG--GYSPYPP------ 518
            ..|.........|:|..:|.  :|..|:   :.|.|    .|...| |||  ||.|.||
Zfish   156 FQGKRIHVQISKSRPRGEED--DYGHPDAGYWPPRYPGERPEPPGY-PRGRYGYPPGPPPPPPPP 217

  Fly   519 ---RGGYRGRGG---------------YRGRGRGMYHYHNDVHR------PPHPGSLAGSSSSVP 559
               |..|..|..               ||.|..|:.:   |..|      ||.|.|.|.....:
Zfish   218 PPRRSPYPDRAAPAYERQRDVVDYYEKYRARPYGVAY---DDRRPGGIPPPPPPPSSAIMRDRM- 278

  Fly   560 PPGGVEDEWRR----PPGESYDRGARSSSREP---------GVERSRSR-SPLKRARSP 604
            |..|::...||    ||...|.|......|.|         |....||| ||:..:|:|
Zfish   279 PGNGLDPYERRPLPPPPASFYARDRSPIRRAPPAPPAPAGNGYSYERSRLSPVSMSRAP 337

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
nito	NP_001286174.1	RRM	<56..>223	CDD:223796
		RRM1_Spen	98..175	CDD:240754
		RRM2_Spen	312..390	CDD:240755	19/79 (24%)
		RRM3_Spen	397..467	CDD:240756	10/69 (14%)
		SPOC	630..789	CDD:311609
rbm4.3	XP_005172323.1	RRM_SF	23..89	CDD:302621	20/91 (22%)
rbm4.3	XP_005172323.1	RRM_SF	100..164	CDD:302621	12/80 (15%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910