DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment nito and rbm14b

DIOPT Version :9

Sequence 1:	NP_001286174.1	Gene:	nito / 35756	FlyBaseID:	FBgn0027548	Length:	793	Species:	Drosophila melanogaster
Sequence 2:	XP_021333123.1	Gene:	rbm14b / 402858	ZFINID:	ZDB-GENE-040426-2455	Length:	560	Species:	Danio rerio

Alignment Length:	256	Identity:	64/256 - (25%)
Similarity:	99/256 - (38%)	Gaps:	58/256 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   313 TRTLFAGNLEVTIADDELRRIFGKYGVVDDIDIKRPPPGTGNAFAFVRYQNLDMAHRAKIELSG- 376
            |..||.|||.:....:||..||..||.|....:.|       .||||..|....|.||..||:|
Zfish     6 TVKLFVGNLALDTTQEELSAIFESYGQVVSCSVLR-------QFAFVHLQGEGAAERAIRELNGR 63

  Fly   377 QYIGK-FQCKIGYGKVTPATRMWIGGLGAWTSVTQLEREFDRFGAIKKIEYQKGEPYAYIQYETV 440
            ::.|: ...:...|:...:|::::|.|.:..:...|:..|..||  |.:|..|.:.||::..|..
Zfish    64 EFKGRNLVVEESRGRPLHSTKVFVGNLSSMCTTEDLQELFQTFG--KVLECDKVKGYAFVHMENK 126

  Fly   441 EAATAAVKEMRGFPLGG-----------PERRLRTDFAELP-----------GATPAAPFKSSKP 483
            |.|..|::.:.|....|           |.:  :|...::|           |..||.  |.:..
Zfish   127 EDALQAIEALHGTSFKGRPLSVELSKVQPSK--QTPTGKIPCVSCGKQGHYAGECPAG--KPTLE 187

  Fly   484 PYDESA--------------LEYRRPEYDPYYEESA---AYAPRGGYSPYPPRGGYRGRGG 527
            .|...|              |:.::..::..|..|.   .||...|.:    ..|.|..||
Zfish   188 QYQSQAAVLAAAAAAAAGLPLQVQQSVHNSVYNTSTFDPTYAALTGLT----AAGARAEGG 244

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
nito	NP_001286174.1	RRM	<56..>223	CDD:223796
		RRM1_Spen	98..175	CDD:240754
		RRM2_Spen	312..390	CDD:240755	26/78 (33%)
		RRM3_Spen	397..467	CDD:240756	19/80 (24%)
		SPOC	630..789	CDD:311609
rbm14b	XP_021333123.1	RRM1_CoAA	7..75	CDD:241052	25/74 (34%)
		RRM1_2_CoAA_like	84..149	CDD:240789	17/66 (26%)
		AIR1	<150..>187	CDD:331526	7/40 (18%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910