DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment nito and nonA

DIOPT Version :9

Sequence 1:	NP_001286174.1	Gene:	nito / 35756	FlyBaseID:	FBgn0027548	Length:	793	Species:	Drosophila melanogaster
Sequence 2:	NP_727962.1	Gene:	nonA / 32603	FlyBaseID:	FBgn0004227	Length:	742	Species:	Drosophila melanogaster

Alignment Length:	221	Identity:	50/221 - (22%)
Similarity:	86/221 - (38%)	Gaps:	36/221 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   304 VQPEDDPLSTR-----TLFAGNLEVTIADDELRRIFGKYGVVDDIDIKRPPPGTGNAFAFVRYQN 363
            ::|.:.|..|:     .|:.|||...|.|||||.:|..||.:.:|.     ......|.|::...
  Fly   287 LEPVEVPTETKFSGRNRLYVGNLTNDITDDELREMFKPYGEISEIF-----SNLDKNFTFLKVDY 346

  Fly   364 LDMAHRAKIELSGQYIGKFQCKIGYGKVTPATRMWIGGLGAWTSVTQLEREFDRFGAIKKIEY-- 426
            ...|.:||..|.|......|.::.:  ...||.:.:..|..:.|...|.:.|:.||.|::...
  Fly   347 HPNAEKAKRALDGSMRKGRQLRVRF--APNATILRVSNLTPFVSNELLYKSFEIFGPIERASITV 409

  Fly   427 -----QKGEPYAYIQYETVEAATAAVK--EMRGFPLGGPERRLRTDFAELPGATPAAPFKSSKPP 484
                 ..||  ..:::....:|:|.::  ..:.|.|....|....|..|:...|...|
  Fly   410 DDRGKHMGE--GIVEFAKKSSASACLRMCNEKCFFLTASLRPCLVDPMEVNDDTDGLP------- 465

  Fly   485 YDESALEYRRPEYDPYYEESAAYAPR 510
              |.|...:.|:::    :..:..||
  Fly   466 --EKAFNKKMPDFN----QERSIGPR 485

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
nito	NP_001286174.1	RRM	<56..>223	CDD:223796
		RRM1_Spen	98..175	CDD:240754
		RRM2_Spen	312..390	CDD:240755	23/82 (28%)
		RRM3_Spen	397..467	CDD:240756	15/78 (19%)
		SPOC	630..789	CDD:311609
nonA	NP_727962.1	RRM1_p54nrb_like	301..371	CDD:240778	22/74 (30%)
		RRM2_p54nrb_like	377..456	CDD:240779	15/80 (19%)
		NOPS_NONA_like	447..546	CDD:240580	10/52 (19%)
		GBP_C	<508..613	CDD:303769
		coiled coil	584..595	CDD:293879
		coiled coil	603..613	CDD:293879
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45459921
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR23189
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.030