Protein Alignment nito and Rbm15b

DIOPT Version :10

• Sequence 1: NP_610339.1
• Gene: nito / 35756
• FlyBaseID: FBgn0027548
• Length: 793
• Species: Drosophila melanogaster
• Sequence 2: NP_001386249.1
• Gene: Rbm15b / 315988
• RGDID: 1305937
• Length: 887
• Species: Rattus norvegicus
• Alignment Length: 937
• Identity: 316/937 - (33%)
• Similarity: 423/937 - (45%)
• Gaps: 269/937 - (28%)

  Fly     4 HRDGAGADRITIKIHNMKRSASRSPGPAS-RSSLSRNSRSMGRGYDNG--SGVP---GDSPERLS 62
            ||||                  |:.|.|: |:|..|:|.:.|.|...|  ||.|   |.|| |.|
  Rat    66 HRDG------------------RAAGDANHRASSGRSSGAPGGGGRTGKASGDPGAGGASP-RAS 111

  Fly    63 PERMRRRLDRSPSRYGSPHREPYMRGPPPAERPAG--------YKVLCVSALPPKAPDDFIEETL 119
            |      |...|              |||...|||        ||.|.:|:|.|..|.:.:|:.|
  Rat   112 P------LPPPP--------------PPPGAEPAGPGTTAAPEYKTLLISSLSPALPAEHLEDRL 156

  Fly   120 YREYKKFGDFSVRLAHDLD-ERVAYVCFRTPEDAREAKHH--KPRLIIYDKMAIVEPVYKSTTRP 181
            :.::|:||:.|:||:|..: .|||||.||.|:|||||:.|  ..:|::||:...|||||.
  Rat   157 FHQFKRFGEISLRLSHTPELGRVAYVNFRHPQDAREARQHALARQLLLYDRPLKVEPVYL----- 216

  Fly   182 EYRPRGHSMSPPDYERYHYSRSPMGQGVPLDHRRPPIDPYDRYGPPHMHPHAVHPRDYRPLHHDY 246
                ||...|      ...|.|......|     ||       ||    |....|..|.|||..|
  Rat   217 ----RGGGSS------RRSSSSSAAASTP-----PP-------GP----PTPADPLGYLPLHGGY 255

  Fly   247 PH------PPRGPPLHRGGHPHHLHGHAPPHQYAPMRPLAPRPHAPYEKPESKKDKFPNYL---- 301
            .:      |...|||......|.....|.....|....|:......|......:.:..:|.
  Rat   256 QYKQRSLSPVAAPPLREPRARHAAAAFALDAAAAAAVGLSRERALDYYGLYDDRGRPYSYQAVCE 320

  Fly   302 HHVQPEDDPLSTRTLFAGNLEVTIADDELRRIFGKYGVVDDIDIKRPPPGTGNAFAFVRYQNLDM 366
            ..:.||||..:||.||.|||:.::::.||||.|.|||:::::.||||..|.|.|:||:::|||||
  Rat   321 EDLMPEDDQRATRNLFIGNLDHSVSEVELRRAFEKYGIIEEVVIKRPARGQGGAYAFLKFQNLDM 385

  Fly   367 AHRAKIELSGQYIGKFQCKIGYGKVTPATRMWIGGLGAWTSVTQLEREFDRFGAIKKIEYQKGEP 431
            |||||:.:||:.||:...||||||..|.||:|:||||..||:..|.|||||||:|:.|::.||:.
  Rat   386 AHRAKVAMSGRVIGRNPIKIGYGKANPTTRLWVGGLGPNTSLAALAREFDRFGSIRTIDHVKGDS 450

  Fly   432 YAYIQYETVEAATAAVKEMRGFPLGGPERRLRTDFAELPGATPAAPFKSSKPPYDESALEYRRP- 495
            :||||||:::||.||..:|||||||||:||||.|||:                    |.|.|.|
  Rat   451 FAYIQYESLDAAQAACAKMRGFPLGGPDRRLRVDFAK--------------------AEETRYPQ 495

  Fly   496 EYDPYYEESAAYAPRGGYSPYPPR-----GGY-RGR---GGYRGRGRGMYHYHNDVHRPPH---- 547
            :|.|              ||.|..     .|| |.|   ...|.|.|          .|||
  Rat   496 QYQP--------------SPLPVHYELLTDGYTRHRNLDADLRVRDR----------TPPHLLYS 536

  Fly   548 --------------------PGSLAGSSSSVPPPGGVE-------------DEWRRPPGESYDRG 579
                                ..||.|.|.||....|..             :|.|:....|.|||
  Rat   537 DRDRTFLEGDWTSLSKSSDRRNSLEGYSRSVRSRSGERWGADGDRSIAKPWEERRKRRSLSSDRG 601

  Fly   580 --------------------ARSSSREPGVERSRSR------------SPLKRAR---------- 602
                                .|.|.|.|  ||||..            :.|..:|
  Rat   602 RTTHSPYEERSRTKGGGQQSERGSDRTP--ERSRKENHSSEGTKESGSNSLSNSRHSAEERSHHH 664

  Fly   603 ----SPGSDSDTSTR---RNDALASA---------------STVPDVARKCSTVWTGALILKSSL 645
                :|.|.....||   ||.....|               .|:.:.|:.....|.|.|:||:|.
  Rat   665 HHHEAPDSSHGKKTRESERNHRTTEAEPKTLEEPKHETKKLKTLSEYAQTLQLGWNGLLVLKNSC 729

  Fly   646 FPAKFHLTDGDTDIVESLMRDEEGKH---NLRITQRLRLDPPKLDDVQKRI--ASSSSHAIFMGL 705
            ||...|:.:||..::..|::|.....   .|:|.||||||.||||:|.:||  .|.:.:|:.:.:
  Rat   730 FPTSMHILEGDQGVISGLLKDHTSGSKLTQLKIAQRLRLDQPKLDEVTRRIKQGSPNGYAVLLAI 794

  Fly   706 AGSTNDTNCD-----DASVQTRPLRNLVSYLKQKEAAGVISLL---NKETEATGVLYAFPPCDFS 762
            ..:.:....:     :..:|.|.|||||||||||:|||||||.   :|..::||:||||||||||
  Rat   795 QSTPSGPGAEGMPMVEPGLQRRLLRNLVSYLKQKQAAGVISLPVGGSKGRDSTGMLYAFPPCDFS 859

  Fly   763 TELLKRTCHSLTEEGLKEDHLVIVVVR 789
            .:.|:....:|.:  |:|:|:|||:||
  Rat   860 QQYLQSALRTLGK--LEEEHMVIVIVR 884

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nito	NP_610339.1	RRM1_Spen	98..175	CDD:409749	36/79 (46%)
		RRM2_Spen	312..390	CDD:240755	42/77 (55%)
		RRM3_Spen	397..468	CDD:409750	44/70 (63%)
		SPOC_RBM15-like	634..790	CDD:439207	73/169 (43%)
Rbm15b	NP_001386249.1	RRM1_RBM15B	134..215	CDD:409970	36/80 (45%)
		RRM2_RBM15B	325..409	CDD:409972	46/83 (55%)
		RRM3_RBM15B	412..487	CDD:409974	47/74 (64%)
		SF-CC1	568..>704	CDD:273721	24/137 (18%)
		SPOC_RBM15B	718..885	CDD:439213	73/169 (43%)