DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG2915 and Agbl3

DIOPT Version :9

Sequence 1:	NP_610338.1	Gene:	CG2915 / 35754	FlyBaseID:	FBgn0033241	Length:	453	Species:	Drosophila melanogaster
Sequence 2:	NP_001276585.1	Gene:	Agbl3 / 76223	MGIID:	1923473	Length:	1006	Species:	Mus musculus

Alignment Length:	469	Identity:	92/469 - (19%)
Similarity:	153/469 - (32%)	Gaps:	158/469 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 CVAMAASGTNLDSGICPVAGDSGCRGNPPDQARYDNYRIYNV------EFENQEQIELFQKLEEQ 80
            |...:..|.|..|...||   ..|......:||:::..:..|      |:|...:.:||.....|
Mouse   150 CFVYSRVGGNRTSLKQPV---DNCDNTLVFEARFESGNLQKVVKVADHEYELTVRPDLFTNKHTQ 211

  Fly    81 SDSLTFIGHAREVGQKLSIL----------------------VAAHRVA--DIADLLKTYK---- 117
            ...........|:..:.:|:                      ...|.:.  .|.|.:|.||
Mouse   212 WYYFQVTNTQAEIVYRFTIVNFTKPASLYNRGMKPLFYSEKEAKTHNIGWQRIGDQIKYYKNNLG 276

  Fly   118 --VKHRV-LTYNFQEKIDRNLAEVQPESIDASQLDWQHFFHLKTIYEWL-----DKMVEKY---- 170
              .:|.. ||:.||          .|.|.|.......:.:....:.|:|     |.:..|:
Mouse   277 QDGRHFFSLTWTFQ----------FPHSQDTCYFAHCYPYTYSNLQEYLSGINSDPVRSKFCKIR 331

  Fly   171 -------PNRVTVLDMGSSTQGNAIKGVKLTSNANNKAIFIESGIHARE----WISPAAATYIIN 224
                   .|.|.||.:.:..:         ||::..||:.:.:.:|..|    ||......||:.
Mouse   332 VLCHTLARNMVYVLTITTPLK---------TSDSKRKAVILTARVHPGETNSSWIMKGFLDYILG 387

  Fly   225 QLLTSQDPKVQQLAQDYNWIIFPCVNPDGYKYTFEHDRMWRKNRQLFGTCR----GVDLNRNYPD 285
            .   |.|.::  |...:.:.:.|.:||||.               :.|..|    |.||||||
Mouse   388 D---SSDARL--LRDTFIFKVVPMLNPDGV---------------IVGNYRCSLAGRDLNRNY-- 430

  Fly   286 HWNSTGSSSDPTRYDFAGPSAGSELETKRLIDFIRANAGKEQIKTYIALHSYS-QMLMFPYG--- 346
              .|....|.|           |...|:.:|:.:..   |.::..|..||.:| :..:|.||
Mouse   431 --TSLLKESFP-----------SVWYTRNMINRLME---KREVILYCDLHGHSRKQNIFMYGCDG 479

  Fly   347 ---------YTKERV------SNYDDLQEFGKKASAAIKAENGRDYVSGSLFETIYPSSGGSMDW 396
                     |.::|:      .|..::..|........|::.|               :|..:.|
Mouse   480 SSRSKTKGLYLQQRIFPLMLSKNCPNIFSFSACKFNVQKSKEG---------------TGRVVMW 529

  Fly   397 AHSEAGIPIAYTFE 410
               :.||..::|.|
Mouse   530 ---KMGIRNSFTLE 540

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2915	NP_610338.1	MpaA	50..433	CDD:225421	85/441 (19%)
		Propep_M14	63..133	CDD:280416	19/106 (18%)
		M14_CP_A-B_like	153..446	CDD:199844	61/301 (20%)
Agbl3	NP_001276585.1	M14_AGBL2-3_like	315..576	CDD:133117	60/291 (21%)
Agbl3	NP_001276585.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	790..810
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2866
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810