DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2915 and Cpa3

DIOPT Version :9

Sequence 1:	NP_610338.1	Gene:	CG2915 / 35754	FlyBaseID:	FBgn0033241	Length:	453	Species:	Drosophila melanogaster
Sequence 2:	NP_062173.1	Gene:	Cpa3 / 54242	RGDID:	2390	Length:	417	Species:	Rattus norvegicus

Alignment Length:	403	Identity:	134/403 - (33%)
Similarity:	215/403 - (53%)	Gaps:	24/403 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    54 RYDNYRIYNVEFENQEQIELFQKLEEQSDSLTF----IGHAREVGQKLSILVAAHRVADIADLLK 114
            ::|..:::.|:.::::|..:.:.| .|:..|.|    ..|...|...:...|.......|...|:
  Rat    20 QFDREKVFRVKLQDEKQASILKNL-TQTIELDFWYPDAIHDIAVNMTVDFRVTEKESQTIQSTLE 83

  Fly   115 TYKVKHRVLTYNFQEKIDRNL---AEVQPESIDASQLDWQHFFHLKTIYEWLDKMVEKYPNRVTV 176
            .:|:.:.:|..:.||:||:..   .|:......|...||      ..|..|.:|||||:|..|:.
  Rat    84 QHKMDYEILINDLQEEIDKQFDVKEEIAGRHSYAKYNDW------NKIVSWTEKMVEKHPEMVSR 142

  Fly   177 LDMGSSTQGNAIKGVKL-TSNANNKAIFIESGIHAREWISPAAATYIINQLLTS--QDPKVQQLA 238
            :.:||:.:.|.:..:|: ..:...||||::.|||||||:|||...:.:.|...|  ::..:.:|.
  Rat   143 IKIGSTVEDNPLYVLKIGRKDGERKAIFMDCGIHAREWVSPAFCQWFVYQAAKSYGKNKIMTKLL 207

  Fly   239 QDYNWIIFPCVNPDGYKYTFEHDRMWRKNRQL--FGTCRGVDLNRNYPDHWNSTGSSSDPTRYDF 301
            ...|:.:.|..|.|||.:::..||||||||..  ..||.|.|||||:...|:|:.::.:|....:
  Rat   208 DRMNFYVLPVFNVDGYIWSWTKDRMWRKNRSKNPNSTCIGTDLNRNFDVSWDSSPNTDNPCLSVY 272

  Fly   302 AGPSAGSELETKRLIDFIRANAGKEQIKTYIALHSYSQMLMFPYGYTKERVSNYDDLQEFGKKAS 366
            .||:..||.|||.:.:|||::.  ..||.||..|||||||:||||||.:...|:.||.:..:.|:
  Rat   273 RGPAPESEKETKAVTNFIRSHL--NSIKAYITFHSYSQMLLFPYGYTIKLPPNHQDLLKVARIAT 335

  Fly   367 AAIKAENGRDYVSGSLFETIYPSSGGSMDWAHSEAGIPIAYTFELRGPPDSQDLFILPAVEIQPT 431
            ..:.:.....|:.|.:..|||.:||.|:|||: :.||...:.||||....|.  |:||...|:||
  Rat   336 DVLSSRYETRYIYGPIASTIYKTSGSSLDWAY-DLGIKHTFAFELRDKGKSG--FLLPESRIKPT 397

  Fly   432 ASEAFTAIRAIVE 444
            ..|...:::.|.:
  Rat   398 CKETMLSVKFIAK 410

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2915	NP_610338.1	MpaA	50..433	CDD:225421	132/390 (34%)
		Propep_M14	63..133	CDD:280416	16/73 (22%)
		M14_CP_A-B_like	153..446	CDD:199844	112/297 (38%)
Cpa3	NP_062173.1	Propep_M14	28..102	CDD:280416	16/74 (22%)
Cpa3	NP_062173.1	Peptidase_M14_like	114..413	CDD:299699	115/308 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166351626
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2866
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D208397at33208
OrthoFinder	1	1.000	-	-		FOG0000056
OrthoInspector	1	1.000	-	-		mtm8990
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X86
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	9	8.750