DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG2915 and agbl5

DIOPT Version :9

Sequence 1:	NP_610338.1	Gene:	CG2915 / 35754	FlyBaseID:	FBgn0033241	Length:	453	Species:	Drosophila melanogaster
Sequence 2:	XP_017210489.1	Gene:	agbl5 / 445479	ZFINID:	ZDB-GENE-040822-29	Length:	886	Species:	Danio rerio

Alignment Length:	513	Identity:	99/513 - (19%)
Similarity:	167/513 - (32%)	Gaps:	180/513 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 VAMAASGTNLDSG---------ICPVAGDSGCRGNPPDQARYDNYRIYNV---------EFEN-- 67
            |..|...:..|||         ....||:|....:.| |..|:    :||         ||||
Zfish     7 VGSAVFSSRFDSGNLARVERVEASEAAGESSRSASVP-QPDYE----FNVWTRPDCASTEFENGN 66

  Fly    68 ------------------------QEQIELF--------------QKLEEQSDSLTFIGHAREVG 94
                                    .:|.:|:              .:.|...|..||     |:.
Zfish    67 RSWFYFSVRGLLPGKLLKINMMNMNKQSKLYTQGMAPFVRTLPVKTRWERVRDRPTF-----EMS 126

  Fly    95 QKLSILVAAHRVADIADLLKTYKVKHRV-----------LTYNFQEKIDRNLAEVQPESIDASQL 148
            ....||...||:.|:..:...:...:..           |.:.|......:.|...||||
Zfish   127 DSQFILSFVHRLLDVRGVTTYFSFCYPFSYAECQDMMLQLDHKFLSSTSTHTACSPPESI----- 186

  Fly   149 DWQHFFHLKTIYEWLDKMVEKYPNRVTVLDMGSSTQG----------------NAIKGVKLTSNA 197
                ::|.:.:...||      .:||.::.: ||..|                :..:..:.|
Zfish   187 ----YYHRELLCHSLD------GHRVDLITV-SSCHGLLEEREPRLDKLFPDLSTARSHRFT--- 237

  Fly   198 NNKAIFIESGIHAREWISPAAATYIINQLLTSQDPKVQQLAQDYNWIIFPCVNPDGYKYTFEHDR 262
            ..:..|:.|.:|..|..|.......:|.:|:.:||:.|.|.:.:.:.:.|.:||||  ....|.|
Zfish   238 GKRVFFVSSRVHPGETPSSFVFNGFLNFILSQEDPRAQTLRRMFVFKLIPMLNPDG--VVRGHYR 300

  Fly   263 MWRKNRQLFGTCRGVDLNRNY----PD-----------------H---WNSTGSSSDPTRYDFAG 303
            .         ..|||:|||.|    ||                 |   .:::||:...:......
Zfish   301 T---------DSRGVNLNRQYVNPSPDLHPSIYGAKSLMLYHHIHNRLGHASGSALKTSNQSNTS 356

  Fly   304 PSAGSELETKRLIDFIRANAGKEQIKTYIALHSYSQMLMFPYGYTKERVSNYDDLQEFGKKASAA 368
            |...:..|.:|.::.:. .|.:.:..|:    ..|::.|              .|:|..:|:...
Zfish   357 PPVATPTERERCMNLLN-EAERGEGPTF----DLSEIPM--------------QLEESWEKSGVQ 402

  Fly   369 IKAENGRDYVSGSLFETIYPSSGGSMDWAHSEAGIP----IAYTFELRGPPDSQDLFI 422
            .:||:..:..|.        .|.|..:.|.||...|    :||..:|.|....:..|:
Zfish   403 REAEHSDENESA--------QSRGETNSAPSEQVPPQESGVAYYIDLHGHASKRGCFM 452

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2915	NP_610338.1	MpaA	50..433	CDD:225421	91/477 (19%)
		Propep_M14	63..133	CDD:280416	19/129 (15%)
		M14_CP_A-B_like	153..446	CDD:199844	63/314 (20%)
agbl5	XP_017210489.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2866
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810