DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2915 and Cpa5

DIOPT Version :9

Sequence 1:	NP_610338.1	Gene:	CG2915 / 35754	FlyBaseID:	FBgn0033241	Length:	453	Species:	Drosophila melanogaster
Sequence 2:	NP_001002808.2	Gene:	Cpa5 / 408212	RGDID:	1303098	Length:	436	Species:	Rattus norvegicus

Alignment Length:	410	Identity:	128/410 - (31%)
Similarity:	220/410 - (53%)	Gaps:	17/410 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    52 QARYDNYRIYNVEFENQEQIELFQKLEEQSDSLT--FIGHAREVGQKLSILVAAHRVADIADLLK 114
            |..:...::..|..:|::|:.|.:.||.|.....  :.|.||. ...:.:.|....:..:...||
  Rat    34 QVNFTGDQVLRVLAKNEKQLSLLRDLEIQKPQKVDFWRGPARP-SLPVDMRVPFSELPSVKAYLK 97

  Fly   115 TYKVKHRVLTYNFQEKIDRN---LAEVQPESIDASQLDWQHFFHLKTIYEWLDKMVEKYPNRVTV 176
            ::.:.:.|:..:.|..:|..   :|..:......:...:..:..|:.||.|:|..|.::.|.|:.
  Rat    98 SHGLAYSVMIKDIQVLLDEERDAMARSRRLERSTNGFSYSSYHTLEEIYNWIDNFVAEHSNLVSK 162

  Fly   177 LDMGSSTQGNAIKGVKL-TSNANNKAIFIESGIHAREWISPAAATYIINQLLT--SQDPKVQQLA 238
            :.:|.|.:..:|..:|. |...|..||:|::|||:||||:.|...:|..:::.  |:|..::::.
  Rat   163 IHIGKSFENRSILVLKFSTGGPNRTAIWIDTGIHSREWITHATGIWISQKIVNAYSKDHVLKKVL 227

  Fly   239 QDYNWIIFPCVNPDGYKYTFEHDRMWRKNRQLFG--TCRGVDLNRNYPDHWNSTGSSSDPTRYDF 301
            ...:..|....||||:.:|...:|:||||:.:..  .|.|||||||:...:...||:.:|....:
  Rat   228 NTMDIFIEIVTNPDGFAFTHSMNRLWRKNKSIQPGIVCVGVDLNRNWRTGFGGNGSNKNPCSETY 292

  Fly   302 AGPSAGSELETKRLIDFIRANAGKEQIKTYIALHSYSQMLMFPYGYTKERVSNYDDLQEFGKKAS 366
            .||:..||.|...::.||   .|....|..|::||||||:|:|||::.|.|.|:.:|.|..|.|.
  Rat   293 RGPAPESEPEVAAIVAFI---TGHGNFKAMISIHSYSQMVMYPYGHSLEPVPNHKELFELAKDAV 354

  Fly   367 AAIKAENGRDYVSGSLFETIYPSSGGSMDWAHSEAGIPIAYTFELRGPPDSQDLFILPAVEIQPT 431
            .|:...:|.:|:.||:..|:|.:||.::|||: ::||..|::||||  ...|..|:|||.:|.||
  Rat   355 KALYKVHGMEYIFGSISTTLYSASGITVDWAY-DSGIKYAFSFELR--DTGQYGFLLPASQIVPT 416

  Fly   432 ASEAFTAIRAIVEAAAEKGY 451
            |.|.:.|:|.|::......|
  Rat   417 AEETWMALRTIMKHTLNHPY 436

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2915	NP_610338.1	MpaA	50..433	CDD:225421	122/390 (31%)
		Propep_M14	63..133	CDD:280416	15/71 (21%)
		M14_CP_A-B_like	153..446	CDD:199844	109/297 (37%)
Cpa5	NP_001002808.2	Propep_M14	48..117	CDD:396700	15/69 (22%)
Cpa5	NP_001002808.2	M14_CPA	134..434	CDD:349442	109/305 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166351674
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2866
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D208397at33208
OrthoFinder	1	1.000	-	-		FOG0000056
OrthoInspector	1	1.000	-	-		mtm8990
orthoMCL	1	0.900	-	-		OOG6_100142
Panther	1	1.100	-	-	O	PTHR11705
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X86
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	11	10.750