DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2915 and CG8560

DIOPT Version :9

Sequence 1:	NP_610338.1	Gene:	CG2915 / 35754	FlyBaseID:	FBgn0033241	Length:	453	Species:	Drosophila melanogaster
Sequence 2:	NP_001261516.1	Gene:	CG8560 / 38830	FlyBaseID:	FBgn0035781	Length:	418	Species:	Drosophila melanogaster

Alignment Length:	406	Identity:	132/406 - (32%)
Similarity:	212/406 - (52%)	Gaps:	20/406 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    55 YDNYRIYNVEFENQEQIELFQKLEEQSDSLTFIGHAREVGQKLSILVAAHRVADIADLLKTYKVK 119
            ||.|:||::...|..:.:|..:| ..:::..|....|.:.....::|..........||:.|.|.
  Fly    21 YDGYKIYDINARNAFEKQLLLRL-SGNEAYDFFDLPRSLDASSRVMVKPEDQEGFEHLLEKYGVN 84

  Fly   120 HRVLTYNFQEKIDRNLAEVQPE------SIDASQLDWQHFFHLKTIYEWLDKMVEKYPNRVTVLD 178
            :.|:..||.|.:.:...|.|.:      |.:.| :.::.|.....|..:||::...||:||:|..
  Fly    85 YSVINENFGESLRQERDENQNQRLMNLRSAERS-VSFKAFHRHAEINAYLDELAAAYPSRVSVQV 148

  Fly   179 MGSSTQGNAIKGVKLTSNANNK----AIFIESGIHAREWISPAAATYIINQLLTSQDPKVQQLAQ 239
            .|.|.:...||.:.:| |.:.|    .:|:::||||||||:.|.|.|:|:||:.:.... .:|.:
  Fly   149 AGKSYENRDIKTITIT-NGDGKTGKNVVFLDAGIHAREWIAHAGALYVIHQLVENFAAN-SELLK 211

  Fly   240 DYNWIIFPCVNPDGYKYTFEHDRMWRKNRQ-LFGTCRGVDLNRNYPDHWNSTGSSSDPTRYDFAG 303
            |::|:|.|.||||||:|:....|||||.|: :...|.|.|.|||:..||...|:||......|.|
  Fly   212 DFDWVILPVVNPDGYEYSHTTTRMWRKTRKPISSACYGTDANRNFDFHWGEVGASSYSCSDTFKG 276

  Fly   304 PSAGSELETKRLIDFIRANAGKEQIKTYIALHSYSQMLMFPYGYTKERVSNYDDLQEFGKKASAA 368
            .:|.||.||:.:.|.:.:..|:.  |.|:.||||...|::|:|:|....|::.|..|..:..:.|
  Fly   277 ETAFSEPETQLIRDILLSLTGRG--KFYLTLHSYGNYLLYPWGWTSALPSSWRDNDEVAQGGADA 339

  Fly   369 IKAENGRDYVSGSLFETIYPSSGGSMDWAHSEAGIPIAYTFELRGPPDSQDLFILPAVEIQPTAS 433
            ||:..|..|..||....:|.::|||.|:|...|..|::.|.||   |.....|.....:|:...|
  Fly   340 IKSATGTKYTVGSSTNVLYAAAGGSDDYAFGVANFPVSITMEL---PAGGTGFNPSTSQIEGFVS 401

  Fly   434 EAFTAIRAIVEAAAEK 449
            |.:..|:|:.:..|:|
  Fly   402 ETWVGIKAMAQKVADK 417

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2915	NP_610338.1	MpaA	50..433	CDD:225421	126/388 (32%)
		Propep_M14	63..133	CDD:280416	14/69 (20%)
		M14_CP_A-B_like	153..446	CDD:199844	107/297 (36%)
CG8560	NP_001261516.1	Propep_M14	29..98	CDD:280416	14/69 (20%)
CG8560	NP_001261516.1	M14_CP_A-B_like	123..414	CDD:199844	107/297 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45466976
Domainoid	1	1.000	158	1.000	Domainoid score	I1007
eggNOG	1	0.900	-	-		E1_COG2866
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	239	1.000	Inparanoid score	I2114
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D208397at33208
OrthoFinder	1	1.000	-	-		FOG0000056
OrthoInspector	1	1.000	-	-		otm46992
orthoMCL	1	0.900	-	-		OOG6_100142
Panther	1	1.100	-	-	P	PTHR11705
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	10	9.800