DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2915 and CG8563

DIOPT Version :9

Sequence 1:	NP_610338.1	Gene:	CG2915 / 35754	FlyBaseID:	FBgn0033241	Length:	453	Species:	Drosophila melanogaster
Sequence 2:	NP_001261515.1	Gene:	CG8563 / 38826	FlyBaseID:	FBgn0035777	Length:	440	Species:	Drosophila melanogaster

Alignment Length:	456	Identity:	116/456 - (25%)
Similarity:	201/456 - (44%)	Gaps:	66/456 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 WLVILC-VAMAASGTNLDSGICPVAGDSGCRGNPPDQARYDNYRIYNVEFENQEQIELFQKLEEQ 80
            |..|:| :|:...|         :||    .|...:.|.|:.|..|.|:..::...:....|:..
  Fly     2 WQGIVCSLALCLVG---------LAG----LGIANNLAGYEGYTKYTVQHGDENAFKYMVDLQTN 53

  Fly    81 SDSLTF-----------IGHAR--EVGQKLSILVAAHRVADIADLLKTYKVKHRVLTYNFQEKID 132
            ...|.|           :...|  :....||.|..::.:..:.:|:...:........|:    |
  Fly    54 DAELDFWLLTRNSSVLTVSPRRKTQFEASLSSLGVSYEMQPLMELMAALQANSSFADDNY----D 114

  Fly   133 RNLAEVQPESIDASQLD-----------WQHFFHLKTIYEWLDKMVEKYPNRVTVLDMGSSTQGN 186
            ....|.|.:..:.::..           :.|:.....:..::..:..:||.......:|.|.:|.
  Fly   115 GEYEECQQDECEQAERPRRRTRRQARGFFSHYPRYHEVLSFMSGLAARYPQFCRYESLGRSNEGR 179

  Fly   187 AIKGVKLTSNAN---NKAIFIESGIHAREWISPAAATYIINQLLTSQDPKVQQLAQDYNWIIFPC 248
            .|..:.::.|:.   .:..:|::..|.||||:.....|:..:||::.....:.| ||....:.|.
  Fly   180 HIAALSISLNSRVRPRRVAYIQAATHGREWITTQTVLYLAYELLSNLRAFTRVL-QDVEIFLVPL 243

  Fly   249 VNPDGYKYTFEHDRMWRKNRQLFG--TCRGVDLNRNYPDHWNSTGSSSDPTRYDFAGPSAGSELE 311
            ||||||:||...||.|||||..:.  :|.|||:|||:.:|||..|:|.:.....::|.:..||.|
  Fly   244 VNPDGYEYTHTTDRFWRKNRHRYAGHSCSGVDINRNFGNHWNYQGASQNLCSEVYSGTAPNSEPE 308

  Fly   312 TKRLIDFIRANAGKEQIKTYIALHSYSQMLMFPYGYTKERVSNYDDLQEFGKKASAAIKAEN--- 373
            |..::.::..|  :.::|..:.:||:.:.:.:||||.|..|.     ...|...|.|::|.|
  Fly   309 TSAVVRYLEFN--RNRVKLSLDVHSFGKFIFYPYGYAKNTVP-----PTVGTLRSVALRAANQIG 366

  Fly   374 ---GRDYVSGSLFETIYPSSGGSMDWAHSEAGIPIAYTFELRGPPDSQDLFILPAVEIQPTASEA 435
               |..|.:|:....:|.:||...|:|:...|||::||.||.|     |.|.:||.:|.....|.
  Fly   367 RYRGTRYTTGTSASILYEASGSLDDFAYGNLGIPLSYTLELPG-----DEFHVPAHDIIHVCKET 426

  Fly   436 F 436
            |
  Fly   427 F 427

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2915	NP_610338.1	MpaA	50..433	CDD:225421	106/417 (25%)
		Propep_M14	63..133	CDD:280416	10/82 (12%)
		M14_CP_A-B_like	153..446	CDD:199844	90/295 (31%)
CG8563	NP_001261515.1	M14_CP_A-B_like	146..437	CDD:199844	90/295 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45466947
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2866
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D208397at33208
OrthoFinder	1	1.000	-	-		FOG0000056
OrthoInspector	1	1.000	-	-		otm46992
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11705
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	7	6.850