DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2915 and CG18585

DIOPT Version :9

Sequence 1:	NP_610338.1	Gene:	CG2915 / 35754	FlyBaseID:	FBgn0033241	Length:	453	Species:	Drosophila melanogaster
Sequence 2:	NP_001260213.1	Gene:	CG18585 / 34041	FlyBaseID:	FBgn0031929	Length:	422	Species:	Drosophila melanogaster

Alignment Length:	440	Identity:	159/440 - (36%)
Similarity:	242/440 - (55%)	Gaps:	28/440 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 WLVILCVAMAASGTNLDSGICPVAGDSGCRGNPPDQARYDNYRIYNVEFENQEQIELFQKLEEQS 81
            ||:...||:.::|...||                .:.||||:|:|.:..:|:.|:...:|:.|.:
  Fly     5 WLLATLVALTSAGILKDS----------------PKERYDNFRVYKLTIQNKIQLAAIEKIGELT 53

  Fly    82 DSLTFIGHAREVGQKLSILVAAHRVADIADLLKTYKVKHRVLTYNFQEKIDRNLAEVQPESIDAS 146
            ..........|..:::.|:|:...:....:|||...:...::..|.||:||..  :|.| :.|::
  Fly    54 KKYNIWKEYDERSRQIDIMVSPGELNHFQELLKFNNISSELMIENVQERIDEE--QVTP-TADSA 115

  Fly   147 QLDWQHFFHLKTIYEWLDKMVEKYPNRVTVLDMGSSTQGNAIKGVKLTSNANNKAIFIESGIHAR 211
            ...|..::.|:.|..|||:::..||:......:|.|.:|..|:|:|::..|.|..|||||.||||
  Fly   116 TFGWTKYYELEEIEAWLDEILNAYPSVTEEFIVGKSYEGRTIRGIKISHKAGNPGIFIESNIHAR 180

  Fly   212 EWISPAAATYIINQLLTSQDPKVQQLAQDYNWIIFPCVNPDGYKYTFEHDRMWRKNRQLFGT--C 274
            |||:.|:||:.|||||||:|..|:.||.:|:|.|.|..|.||::|:.:.||||||.||...|  |
  Fly   181 EWITSASATWFINQLLTSEDADVRSLADNYDWHIIPVFNVDGFEYSHKKDRMWRKTRQPHATNAC 245

  Fly   275 RGVDLNRNYPDHW-NSTGSSSDPTRYDFAGPSAGSELETKRLIDFIRANAGKEQIKTYIALHSYS 338
            .|.|.|||:..:| .:.|:|.:|....|||.:..||.|.|.|::::  ...::||..||:.|||.
  Fly   246 IGADANRNFDSYWLQNNGASDNPCSETFAGDNPESEPEAKALVEYL--TKIQDQISVYISFHSYG 308

  Fly   339 QMLMFPYGYTKERV-SNYDDLQEFGKKASAAIKA-ENGRDYVSGSLFETIYPSSGGSMDWAHSEA 401
            |.|:.|||:|.|.. .||:|:...||..:.||:| ..|..|..||..:.:|.::|.|:||..:|.
  Fly   309 QYLLSPYGHTNEEFPENYNDILTIGKAFADAIEALPYGTVYQYGSTADVLYVATGTSVDWVFNEL 373

  Fly   402 GIPIAYTFELRGPPDSQDLFILPAVEIQPTASEAFTAIRAIVEAAAEKGY 451
            |..|.||.|.|  ...:..||||.|:|.|...|....:.|::|...|.||
  Fly   374 GKKIGYTIEYR--DKGRYGFILPPVQIIPNCEELMVGMLALIEKTKELGY 421

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2915	NP_610338.1	MpaA	50..433	CDD:225421	146/387 (38%)
		Propep_M14	63..133	CDD:280416	14/69 (20%)
		M14_CP_A-B_like	153..446	CDD:199844	124/297 (42%)
CG18585	NP_001260213.1	Propep_M14	34..105	CDD:280416	14/70 (20%)
CG18585	NP_001260213.1	M14_CP_A-B_like	122..415	CDD:199844	123/296 (42%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45467016
Domainoid	1	1.000	158	1.000	Domainoid score	I1007
eggNOG	1	0.900	-	-		E1_COG2866
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	239	1.000	Inparanoid score	I2114
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D208397at33208
OrthoFinder	1	1.000	-	-		FOG0000056
OrthoInspector	1	1.000	-	-		mtm4737
orthoMCL	1	0.900	-	-		OOG6_100142
Panther	1	1.100	-	-	P	PTHR11705
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X86
	11	10.800