DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG2915 and CG8945

DIOPT Version :9

Sequence 1:	NP_610338.1	Gene:	CG2915 / 35754	FlyBaseID:	FBgn0033241	Length:	453	Species:	Drosophila melanogaster
Sequence 2:	NP_573190.1	Gene:	CG8945 / 32693	FlyBaseID:	FBgn0030815	Length:	1430	Species:	Drosophila melanogaster

Alignment Length:	531	Identity:	135/531 - (25%)
Similarity:	230/531 - (43%)	Gaps:	119/531 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MGNKIINMPAARIGTQ----WLVILCVAMAASGTNLDSGICPVAGDSGCRGNPPDQARYDNYRIY 61
            :.:.|:|...:.|.|.    .|..|...|...||...:       .:..|.:.|.:..||.|:|:
  Fly   930 LAHHIVNSTGSAISTSTSNPLLQALATRMTTRGTTSTT-------TTTSRPDVPRRISYDKYQIW 987

  Fly    62 NVEFENQEQIELFQKLEEQSDSLTFIGHAREVGQKL------------SILVAAHRVADIADLLK 114
            .::.:::||:...::.::..|           |.||            .:||....:.|....|.
  Fly   988 RLKPQDEEQVRALEEFKKGED-----------GVKLQWLKGPSLRGLTDVLVPPKMLVDFQGTLN 1041

  Fly   115 TYKVKHRVLTYNFQEKIDRNLAE---------VQPESIDASQLDWQHFFHLKTIYEWLDKMVEKY 170
            ...:.|.||.::..:.|...|.:         .:|.......:.|..:.:...|.::|:.:..::
  Fly  1042 YEGIAHEVLIFDVGKAIAYELTKEDYLQTTRPSKPRPTAPPPMTWNRYHNHDEIVKYLETVRMRH 1106

  Fly   171 PNRVTVLDMGSSTQGNAIKGVKLTSN-----ANN------------------KAIFIESGIHARE 212
            |..|.::.:|.|.:|..:..||:.|.     |||                  .|:|:|:|.....
  Fly  1107 PQLVELIHIGRSFEGRPLIVVKIESKQTAAAANNDGLHTIKRPKRKRKSGQANAVFVEAGAQGLA 1171

  Fly   213 WISPAAATYIINQLL----TSQDPKVQQLAQDYNWIIFPCVNPDGYKYTFEHDRMWRKNRQLFGT 273
            ||.|||||::|.:||    |::..:..:..::..|.|.|.:|||||.|:.|:||.|:|:|....|
  Fly  1172 WIGPAAATWMIAELLRLMKTNKSNEDVEFIRNTTWYIMPVLNPDGYAYSHEYDRFWKKSRSQHQT 1236

  Fly   274 -----------------------CRGVDLNRNYPDHWNSTGSSSDPTRYDFAGPSAGSELETKRL 315
                                   |.||||:||:..||...|||..|....:|||:..||.|||.:
  Fly  1237 PPPSGLLDSAMTWLQQKRGPDKVCYGVDLDRNWLYHWGKRGSSKAPCNEFYAGPAPFSEPETKAV 1301

  Fly   316 IDFIRANAGKEQIKTYIALHSYSQMLMFPY----GYTKERVSNY--------DDLQEFGKKASAA 368
            .:|:...  :.|||.||:|.:|.|::.:|.    .:..||:.::        |.|::.|.|:...
  Fly  1302 SEFLMDY--RTQIKLYISLQAYGQVISYPVKANSTFNSERLDDFLDVAMVGTDGLRKKGSKSRYK 1364

  Fly   369 IKAENGRDYVSGSLFETIYPSSGGSMDWAHSEAGIPIAYTFELRGPPDSQDLFILPAVEIQPTAS 433
            :.|.|          :.|...||.:..:|..|.|||.:||.:|  ..:....::||:..|:|||.
  Fly  1365 VDASN----------DLIEQRSGCADAFAAYEIGIPFSYTLQL--ADNGVHGYLLPSSAIEPTAR 1417

  Fly   434 EAFTAIRAIVE 444
            :||..|..:::
  Fly  1418 DAFEIISGMLD 1428

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2915	NP_610338.1	MpaA	50..433	CDD:225421	121/465 (26%)
		Propep_M14	63..133	CDD:280416	14/81 (17%)
		M14_CP_A-B_like	153..446	CDD:199844	103/354 (29%)
CG8945	NP_573190.1	Propep_M14	988..1058	CDD:280416	13/80 (16%)
CG8945	NP_573190.1	M14_CP_A-B_like	1089..1430	CDD:199844	103/354 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2866
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D208397at33208
OrthoFinder	1	1.000	-	-		FOG0000056
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11705
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.920