DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2915 and cpa1

DIOPT Version :9

Sequence 1:	NP_610338.1	Gene:	CG2915 / 35754	FlyBaseID:	FBgn0033241	Length:	453	Species:	Drosophila melanogaster
Sequence 2:	NP_001018318.1	Gene:	cpa1 / 325886	ZFINID:	ZDB-GENE-050522-438	Length:	418	Species:	Danio rerio

Alignment Length:	409	Identity:	128/409 - (31%)
Similarity:	224/409 - (54%)	Gaps:	22/409 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    55 YDNYRIYNVEFENQEQIELFQKLEEQSDSL---TFIGHAREVGQKLSILVAAHRVADIADLLKTY 116
            ::..::..:..:|.|||.|.::|.| :|.|   .::..||| ...:.:.|..|.:..:...|...
Zfish    20 FEGDQVLRINAKNAEQISLLKELTE-ADLLGLDFWMNPARE-SLPVDLHVPFHSLQAVRAFLAYN 82

  Fly   117 KVKHRVLTYNFQEKIDRNLAEVQ-----PESIDASQLDWQHFFHLKTIYEWLDKMVEKYPNRVTV 176
            ::.:.::..|.|:.:|:...::.     |.|.|  ...:..:..|.:|..::|.:|.:..|.|:.
Zfish    83 QIPYHIMIENVQDLVDKEQLQMLKYHGFPRSTD--DFVYTTYHDLDSINLFMDMLVAENQNMVSK 145

  Fly   177 LDMGSSTQGNAIKGVKLTSNANNKAIFIESGIHAREWISPAAATYIINQLLT--SQDPKVQQLAQ 239
            :::|.|.:...:..:|.::.||...|:|::|:|:||||:.|:..:...:::|  .:||.:..:..
Zfish   146 IEIGQSYENRPLNVLKFSTGANRPGIWIDTGLHSREWITHASGIWFAKKIVTDYGRDPVLTDILN 210

  Fly   240 DYNWIIFPCVNPDGYKYTFEHDRMWRKNRQ--LFGTCRGVDLNRNYPDHWNSTGSSSDPTRYDFA 302
            .|:..:....||||..||...||||||.|:  ...:|.|||.|||:...:...||||:|....:.
Zfish   211 SYDIFLEIVANPDGLAYTHSDDRMWRKTRKPNPGSSCVGVDPNRNWETGFGGPGSSSNPCSQTYH 275

  Fly   303 GPSAGSELETKRLIDFIRANAGKEQIKTYIALHSYSQMLMFPYGYTKERVSNYDDLQEFGKKASA 367
            |||..||.|.|.:::|::::.   .:|.::::|||||||::|||||:....:..:|.|..:||::
Zfish   276 GPSIHSEPEVKAIVEFVKSHG---NLKAFLSIHSYSQMLLYPYGYTQTAAKDQAELHELARKATS 337

  Fly   368 AIKAENGRDYVSGSLFETIYPSSGGSMDWAHSEAGIPIAYTFELRGPPDSQDLFILPAVEIQPTA 432
            .:::.....|..||:..|||.:.|.:.|||: |.||..:||||||  ...:..|||||.:|.|||
Zfish   338 ELQSLYNTAYTYGSIITTIYQADGVTTDWAY-EQGIKYSYTFELR--DTGRYGFILPADQILPTA 399

  Fly   433 SEAFTAIRAIVEAAAEKGY 451
            .|.:.|:..|:|......|
Zfish   400 EETWLALMVIMEHIKNNPY 418

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2915	NP_610338.1	MpaA	50..433	CDD:225421	122/389 (31%)
		Propep_M14	63..133	CDD:280416	17/72 (24%)
		M14_CP_A-B_like	153..446	CDD:199844	106/296 (36%)
cpa1	NP_001018318.1	Propep_M14	27..99	CDD:280416	17/73 (23%)
cpa1	NP_001018318.1	Peptidase_M14_like	117..416	CDD:299699	106/304 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170593480
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2866
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D208397at33208
OrthoFinder	1	1.000	-	-		FOG0000056
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100142
Panther	1	1.100	-	-	O	PTHR11705
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X86
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	10	9.750