DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG2915 and CG3097

DIOPT Version :9

Sequence 1:	NP_610338.1	Gene:	CG2915 / 35754	FlyBaseID:	FBgn0033241	Length:	453	Species:	Drosophila melanogaster
Sequence 2:	NP_572259.1	Gene:	CG3097 / 31503	FlyBaseID:	FBgn0029804	Length:	445	Species:	Drosophila melanogaster

Alignment Length:	458	Identity:	142/458 - (31%)
Similarity:	235/458 - (51%)	Gaps:	59/458 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 LVILCVAMAASGTN--------LDSGICPVAGDSGCRGNPPDQARYDN---YRIYNVEFENQEQI 71
            |::|..|:|||..|        ||:...|              .|||.   :||||:....|:::
  Fly    10 LLLLVAAVAASLANELPSNLTLLDANEIP--------------QRYDEAQLWRIYNISEAMQKRV 60

  Fly    72 ELFQKLEEQSDSLTFIGHA-REVGQKLSILVAAHRVADIADLLKTYKVKHRVLTYNFQEKIDRNL 135
            .:.|.||::     |.|:. :|..:.|.|.:|..::......|..:::..::|::|.|..||..|
  Fly    61 PVGQMLEQK-----FGGNIWKENSKFLDISIARDQLKAARSFLSAHRLDPQILSHNIQSMIDEEL 120

  Fly   136 AE-VQPESID---------ASQLDWQHFFHLKTIYEWLDKMVEKYPNRVTVLDMGSSTQGNAIKG 190
            .| :|..|..         .|.:.|:.:..|:|||.::.::..|:||.|.:..:|.:.:|..:|.
  Fly   121 LEGIQSSSFGHGRRTKKAARSSMHWKDYHDLETIYSFMREIRTKFPNIVRLYTIGQTAEGRDLKV 185

  Fly   191 VKLTSN-ANNKAIFIESGIHAREWISPAAATYIINQLLTSQDPKVQQLAQDYNWIIFPCVNPDGY 254
            ::::.| ..||.::|:.|||||||||||..|:|:.||::..:.:...: :...|.|.|.:|||||
  Fly   186 LRISENPRENKKVWIDGGIHAREWISPATVTFILYQLMSDWENQPAHI-RGLTWYIMPVMNPDGY 249

  Fly   255 KYTFEHDRMWRKNR--QLFGTCRGVDLNRNYPDHWNSTGSSSDPTRYDFAGPSAGSELETKRLID 317
            :|:...:|:|||||  .....|.|||||||:...||..|||::|....:.|.:..||.||:.:.:
  Fly   250 EYSRTTNRLWRKNRSPSRRAQCSGVDLNRNFDIGWNGYGSSTNPCSDTYRGSAPASERETRAVAE 314

  Fly   318 FIRANAGKEQIKTYIALHSYSQMLMFPYGYTKERVSNYDDLQEFGKKASAAIKAENGRDYVSGSL 382
            |:...  |..:::|:..|||.||:::|:.|...:|.:...||.....|:..|..:.|..|.:...
  Fly   315 FLAKR--KYNLESYLTFHSYGQMIVYPWAYKAVKVKDASVLQRVSSLAAERILQKTGTSYRAAVT 377

  Fly   383 FETIYPSSGGSMDWAHSEAGIPIAYTFELR-----GPPDSQDLFILPAVEIQPTASEAFTAIRAI 442
            .|.:..:.|||.||:.:..|:...||.|||     |       |:||...|:.||.|.:|.:..:
  Fly   378 HEVLGIAGGGSDDWSRAALGVKYVYTIELRDRGAYG-------FVLPPRFIKDTALEGWTVVETV 435

  Fly   443 VEA 445
            .:|
  Fly   436 AQA 438

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2915	NP_610338.1	MpaA	50..433	CDD:225421	128/404 (32%)
		Propep_M14	63..133	CDD:280416	15/70 (21%)
		M14_CP_A-B_like	153..446	CDD:199844	103/301 (34%)
CG3097	NP_572259.1	Propep_M14	64..118	CDD:280416	14/58 (24%)
CG3097	NP_572259.1	M14_CP_A-B_like	148..439	CDD:199844	103/301 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45466945
Domainoid	1	1.000	158	1.000	Domainoid score	I1007
eggNOG	1	0.900	-	-		E1_COG2866
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	171	1.000	Inparanoid score	I1180
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D208397at33208
OrthoFinder	1	1.000	-	-		FOG0000056
OrthoInspector	1	1.000	-	-		otm46992
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11705
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X86
	10	9.900