DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2915 and SPBC337.07c

DIOPT Version :9

Sequence 1:	NP_610338.1	Gene:	CG2915 / 35754	FlyBaseID:	FBgn0033241	Length:	453	Species:	Drosophila melanogaster
Sequence 2:	NP_595408.1	Gene:	SPBC337.07c / 2541067	PomBaseID:	SPBC337.07c	Length:	497	Species:	Schizosaccharomyces pombe

Alignment Length:	507	Identity:	134/507 - (26%)
Similarity:	212/507 - (41%)	Gaps:	92/507 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 IGTQWLVILCVAMAASGTNLDSGICPVAGDSGCRGNPPDQARYDNYRIYNVEFE--NQEQIELFQ 75
            :.:|.:.:|.:....|...|           |.:.|...::...:|..:|.|..  ::||:...:
pombe    15 LASQIVFVLFLCYGKSSREL-----------GVKWNSDIRSWMTSYVGFNGETAAISEEQLIWAE 68

  Fly    76 KLEEQSDSLTFIGHAREVGQKLSILVAAH-RVADIADLLKTYKVKH---RVLTYNF-----QEKI 131
            |:.:.::.:....|..|......||..|. :..||.|    |...|   |:...||     |.:.
pombe    69 KIPDYNEEIVVRLHLEEENNLSDILQKAQSQNLDIWD----YNFDHVDLRLKEENFDFWKSQYRS 129

  Fly   132 D---RNLAEVQPESI-----------------------------DASQLDWQHFFHLKTIYEWLD 164
            |   .||.|...|||                             ..:.:.::.:.:|::|..||.
pombe   130 DILINNLTETLFESIVPDTTNSPFSTEAFLQAVENGHLNHEMFTSFTDIFFKSYQNLESINSWLR 194

  Fly   165 KMVEKYPNRVTVLDMGSSTQGNAIKGVKLTSN---------ANNKAIFIESGIHAREWISPAAAT 220
            .|...|.:...::.:|.:.:|..|.|:||...         .|.|.|.|:.|.||||||...:..
pombe   195 LMASLYKDLSELVPVGITAEGRTILGLKLNGRHPSDNGEKIRNKKVIIIQGGSHAREWIGIPSVC 259

  Fly   221 YIINQLLT--SQDPKVQQLAQDYNWIIFPCVNPDGYKYTFEHDRMWRKNRQLFGT--CRGVDLNR 281
            |...|||.  ..|..|::|...:.||..|.:|.|||:||:.:||:|.||||....  |.|::|:.
pombe   260 YAAWQLLAKYDSDGHVRKLLDKFEWIFIPVLNVDGYEYTWSNDRLWSKNRQPLNNSECFGINLDA 324

  Fly   282 NYPDHWNSTGSSSDPTRYDFAGPSAGSELETKRLIDFIRANAGKEQIKT--YIALHSYSQMLMFP 344
            |:...:|   .:.||...::.|.|.....||..|.:.|..:..:||.|.  ::.:|||||.:::|
pombe   325 NWAFGFN---GNIDPCSNEYGGLSPFQANETMALFNLITESLSQEQKKVVGFLDVHSYSQSVLWP 386

  Fly   345 YGYTKERVSNYDDLQEFGKKASAAIK---AENGRDY------VSGSLFETIYPSSGGSMDWAHSE 400
            |.||.:...  .|.:.|.:.|...:|   ..|.|.|      :....|...| ..|.::||.:..
pombe   387 YAYTCDLFP--PDTENFEELAIGLVKELHRVNSRYYTYQQACIPYDGFHKHY-LPGTAIDWVYFA 448

  Fly   401 AGIPIAYTFELRGPPDSQDL-FILPAVEIQPTASEAFTAIRAIVEAAAEKGY 451
            |.:...:...||   |..|. ::|||.:|.|||.|.|..|....|..||..:
pombe   449 ADVAWPFNIRLR---DMGDYGYLLPAKQIVPTAKEFFAMILYYGEFIAEYAF 497

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2915	NP_610338.1	MpaA	50..433	CDD:225421	121/450 (27%)
		Propep_M14	63..133	CDD:280416	19/83 (23%)
		M14_CP_A-B_like	153..446	CDD:199844	99/317 (31%)
SPBC337.07c	NP_595408.1	MpaA	42..479	CDD:225421	121/449 (27%)
SPBC337.07c	NP_595408.1	M14_CP_A-B_like_1	180..492	CDD:199869	99/320 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	158	1.000	Domainoid score	I1007
eggNOG	1	0.900	-	-		E1_COG2866
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	171	1.000	Inparanoid score	I1180
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000056
OrthoInspector	1	1.000	-	-		otm46992
orthoMCL	1	0.900	-	-		OOG6_100142
Panther	1	1.100	-	-	O	PTHR11705
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X86
TreeFam	0	0.000	Not matched by this tool.
	9	8.860