DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2915 and W01A8.6

DIOPT Version :9

Sequence 1:	NP_610338.1	Gene:	CG2915 / 35754	FlyBaseID:	FBgn0033241	Length:	453	Species:	Drosophila melanogaster
Sequence 2:	NP_492003.2	Gene:	W01A8.6 / 189076	WormBaseID:	WBGene00012168	Length:	380	Species:	Caenorhabditis elegans

Alignment Length:	335	Identity:	93/335 - (27%)
Similarity:	152/335 - (45%)	Gaps:	47/335 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   153 FFHLKTIYEWLDKMVEKY--------PNRVTVLDMGSSTQGNAIKGVKLTSNA----NNKAIFIE 205
            ||.|....:|  ...|.|        |:.|.:..:|.:.:|..:.||::...|    ...|::::
Worm    29 FFDLTVYNDW--PQFEDYIKGVAHDNPSFVQLKTIGRTREGRPLLGVRIGKPALPGKRKIAVWLD 91

  Fly   206 SGIHAREWISPAAATYIINQLLTS--QDPKVQQLAQDYNWIIFPCVNPDGYKY----TFEHDRMW 264
            .|.|||||.:...|.|.|.:|:..  .|.|:.:..:..:..:||.:||||:.|    |....|.|
Worm    92 GGNHAREWPAFHVAVYFIEKLVNGYLSDDKITKYVETLDIYVFPVLNPDGFVYSRTSTRAMIRQW 156

  Fly   265 RKNR---QLFGT--------CRGVDLNRNYP---DHWNSTGSSSDPTRYDFAGPSAGSELETKRL 315
            ||||   ...||        |.||||||||.   .|.|.  ..::|...:|.||...||.||:.:
Worm   157 RKNRAPENCTGTGPFQTDICCEGVDLNRNYDIGFSHKNY--PFNNPCSDEFQGPRPFSEPETRAV 219

  Fly   316 IDFIRANAGKEQIKTYIALHSYSQMLMFPYGYTKERV-SNYDDLQEFGKKASAAIKAENGRDYVS 379
            .|||.::....::...:::|::.|:.:.||.|.|... .:..||:....:|:..:.|.....|..
Worm   220 RDFIMSSEIYGRLYALVSMHTHGQLWILPYNYQKRTYPQDIKDLEILANRAADRVFAYRETKYRV 284

  Fly   380 GSLFETIYPSSGGSMDWAHSEAGIPIAYTFELRGPPDSQDLFILPAVEIQ-----PTASEAFTAI 439
            |:..:.:..::||:.||.  :...|..|.:.|..|||.:..|   |.:::     |...|.:..|
Worm   285 GTAADMLGTATGGATDWI--KKNTPTKYVYVLELPPDMKTWF---AFQVKPHWLIPIGKETWLGI 344

  Fly   440 RAIVEAAAEK 449
            ..|.:...|:
Worm   345 EVIFDQVVEE 354

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2915	NP_610338.1	MpaA	50..433	CDD:225421	89/317 (28%)
		Propep_M14	63..133	CDD:280416
		M14_CP_A-B_like	153..446	CDD:199844	92/330 (28%)
W01A8.6	NP_492003.2	Zn_pept	35..337	CDD:214748	86/310 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	220	1.000	Domainoid score	I1500
eggNOG	1	0.900	-	-		E1_COG2866
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG47975
OrthoDB	1	1.010	-	-		D208397at33208
OrthoFinder	1	1.000	-	-		FOG0000056
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100142
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	7.730