DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2915 and Y59C2A.1

DIOPT Version :9

Sequence 1:	NP_610338.1	Gene:	CG2915 / 35754	FlyBaseID:	FBgn0033241	Length:	453	Species:	Drosophila melanogaster
Sequence 2:	NP_494213.2	Gene:	Y59C2A.1 / 173577	WormBaseID:	WBGene00021984	Length:	454	Species:	Caenorhabditis elegans

Alignment Length:	460	Identity:	136/460 - (29%)
Similarity:	222/460 - (48%)	Gaps:	56/460 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 LVILCVAMAASGTNLDSGICPVAGDSGCRGNPPD-QARYDNYRIYNVEFE-NQEQIELFQKLEEQ 80
            ||.:.:.:...|.|             |..|..: :|.|..|.::..:.: :.:.:|..:..:.|
Worm     6 LVPILILVTTYGVN-------------CHENSGEKRADYSGYTLHRFKVDTSSDTMEKLEGYDMQ 57

  Fly    81 SDSLT-----FIGHAREVGQK---LSILVAAHRVADIADLLKTYKVKH-RVLTYNFQEKID---- 132
            .|..|     .|....|..::   ..||||...:.....||.:.::.. ::|..:.|.:|:
Worm    58 LDKTTQTARLLIDIWAEPSKQNPYADILVAPEFLQKFKSLLTSAELSTLKMLEGDIQSQINAERH 122

  Fly   133 ---RNLAEVQPESIDASQLDWQHF----FH-LKTIYEWLDKMVEKYPNRVTVLDMGSSTQGNAIK 189
               ||....:..::..    ||.|    :| ...:.|::..:.|:..:.|.::.:.:|::|.:|.
Worm   123 AMIRNSVRRRKRAMKT----WQEFDTNAYHSYNEMVEFMKLLSEQKSDMVEMVKVATSSEGRSIY 183

  Fly   190 GVKL----TSNANNKAIFIESGIHAREWISPAAATYIINQLLT--SQDPKVQQLAQDYNWIIFPC 248
            |||:    .|.....:|.:::|:||||||:||...::|.:::.  .::|:|....|.::|.|.|.
Worm   184 GVKIHPPGPSPPEKPSIIVDAGVHAREWIAPAVGLFMIRKIVEEYGRNPQVTANLQKFDWYIMPQ 248

  Fly   249 VNPDGYKYTFEHDRMWRKNRQLFGT----CRGVDLNRNYPDHWNSTGSSSDPTRYDFAGPSAGSE 309
            ||||||:|:...||:|||.|....|    |.|.|.|||:...|...|::..|....:.|....||
Worm   249 VNPDGYEYSRTTDRLWRKTRSKNVTVNRWCVGADANRNWGYRWGEAGANRTPCSNIYMGSHPYSE 313

  Fly   310 LETKRLIDFIRANAGKEQIKTYIALHSYSQMLMFPYGYTKERVSNYDDLQEFGKKASAAIKAENG 374
            .|.:.|.:|.........:  ||:||||.|:|:.|:|||.||..||.|.|...|:|:.|||...|
Worm   314 PEIRGLKEFFTWQITNPMV--YISLHSYGQLLLSPWGYTNERTENYQDQQNAAKEAAQAIKNTTG 376

  Fly   375 RDYVSGSLFETIYPSSGGSMDWAHSEAGIPIAYTFELRGPPDSQDLFI--LPAVEIQPTASEAFT 437
            ..|..|::.|.:||:||.|:|:. ...|:|..|..||| |.|:.:.|.  ||...|:.|..|...
Worm   377 VSYSYGTISEMMYPASGTSIDFM-QHRGVPYIYGVELR-PTDNPNSFAFNLPPSYIRATGDEMLA 439

  Fly   438 AIRAI 442
            |:.||
Worm   440 ALNAI 444

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2915	NP_610338.1	MpaA	50..433	CDD:225421	126/417 (30%)
		Propep_M14	63..133	CDD:280416	15/86 (17%)
		M14_CP_A-B_like	153..446	CDD:199844	108/307 (35%)
Y59C2A.1	NP_494213.2	Propep_M14	<69..120	CDD:366995	11/50 (22%)
Y59C2A.1	NP_494213.2	M14_CP_A-B_like	147..441	CDD:349433	104/297 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2866
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG47975
OrthoDB	1	1.010	-	-		D208397at33208
OrthoFinder	1	1.000	-	-		FOG0000056
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100142
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X86
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.730