Protein Alignment CG2915 and CPA3

DIOPT Version :10

• Sequence 1: NP_610338.1
• Gene: CG2915 / 35754
• FlyBaseID: FBgn0033241
• Length: 453
• Species: Drosophila melanogaster
• Sequence 2: NP_001861.2
• Gene: CPA3 / 1359
• HGNCID: 2298
• Length: 417
• Species: Homo sapiens
• Alignment Length: 448
• Identity: 143/448 - (31%)
• Similarity: 229/448 - (51%)
• Gaps: 62/448 - (13%)

  Fly    19 VILCVAMAASGTNLDSGICPVAGDSGCRGNPPDQARYDNYRIYNVEFENQEQIELFQKLEEQSD- 82
            :||.|.:.|  |.|  .|.||              |:|..:::.|:.::::|.::.:.|.:.::
Human     3 LILPVGLIA--TTL--AIAPV--------------RFDREKVFRVKPQDEKQADIIKDLAKTNEL 49

  Fly    83 SLTFIGHAREVGQKLSILVAAHRVAD-----IADLLKTYKVKHRVLTYNFQEKIDRNL---AEVQ 139
            ...:.|....|...:.:   ..||::     |...|...|:.:.:|.::.||:|::..   .::.
Human    50 DFWYPGATHHVAANMMV---DFRVSEKESQAIQSALDQNKMHYEILIHDLQEEIEKQFDVKEDIP 111

  Fly   140 PESIDASQLDWQHFFHLKTIYEWLDKMVEKYPNRVTVLDMGSSTQGNAIKGVKL-TSNANNKAIF 203
            .....|...:|:      .|..|.:||::|||..|:.:.:||:.:.|.:..:|: ..|...||||
Human   112 GRHSYAKYNNWE------KIVAWTEKMMDKYPEMVSRIKIGSTVEDNPLYVLKIGEKNERRKAIF 170

  Fly   204 IESGIHAREWISP---------AAATYIINQLLTSQDPKVQQLAQDYNWIIFPCVNPDGYKYTFE 259
            .:.|||||||:||         |..||..|:::|       :|....|:.|.|..|.|||.:::.
Human   171 TDCGIHAREWVSPAFCQWFVYQATKTYGRNKIMT-------KLLDRMNFYILPVFNVDGYIWSWT 228

  Fly   260 HDRMWRKNR--QLFGTCRGVDLNRNYPDHWNSTGSSSDPTRYDFAGPSAGSELETKRLIDFIRAN 322
            .:|||||||  .....|.|.|||||:...|||..:::||...::.|.:..||.|||.:.:|||::
Human   229 KNRMWRKNRSKNQNSKCIGTDLNRNFNASWNSIPNTNDPCADNYRGSAPESEKETKAVTNFIRSH 293

  Fly   323 AGKEQIKTYIALHSYSQMLMFPYGYTKERVSNYDDLQEFGKKASAAIKAENGRDYVSGSLFETIY 387
            .  .:||.||..|||||||:||||||.:...|::||.:..|..:..:.......|:.|.:..|||
Human   294 L--NEIKVYITFHSYSQMLLFPYGYTSKLPPNHEDLAKVAKIGTDVLSTRYETRYIYGPIESTIY 356

  Fly   388 PSSGGSMDWAHSEAGIPIAYTFELRGPPDSQDL-FILPAVEIQPTASEAFTAIRAIVE 444
            |.||.|:|||: :.||...:.||||   |.... |:||...|:||..|...|::.|.:
Human   357 PISGSSLDWAY-DLGIKHTFAFELR---DKGKFGFLLPESRIKPTCRETMLAVKFIAK 410

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2915	NP_610338.1	Propep_M14	61..133	CDD:460505	14/77 (18%)
		M14_CP_A-B_like	154..444	CDD:349433	116/302 (38%)
CPA3	NP_001861.2	Propep_M14	27..103	CDD:460505	14/78 (18%)
		M14_CPB	114..413	CDD:349443	118/316 (37%)