Protein Alignment CG2915 and CPA1

DIOPT Version :10

• Sequence 1: NP_610338.1
• Gene: CG2915 / 35754
• FlyBaseID: FBgn0033241
• Length: 453
• Species: Drosophila melanogaster
• Sequence 2: NP_001859.1
• Gene: CPA1 / 1357
• HGNCID: 2296
• Length: 419
• Species: Homo sapiens
• Alignment Length: 405
• Identity: 118/405 - (29%)
• Similarity: 216/405 - (53%)
• Gaps: 19/405 - (4%)

  Fly    58 YRIYNVEFENQEQIELFQKLEE-QSDSLTFIGHAREVGQKLSILVAAHRVADIADLLKTYKVKHR 121
            :::..:...::.|::..::||: :...|.|.......|..:.:.|....:..:...|:::.:.:.
Human    23 HQVLRISVADEAQVQKVKELEDLEHLQLDFWRGPAHPGSPIDVRVPFPSIQAVKIFLESHGISYE 87

  Fly   122 VLTYNFQEKIDRNLAEV-----QPESIDASQLDWQHFFHLKTIYEWLDKMVEKYPNRVTVLDMGS 181
            .:..:.|..:|....::     :..|.|.  .::..:..|:.||::||.:|.:.|:.|:.:.:|:
Human    88 TMIEDVQSLLDEEQEQMFAFRSRARSTDT--FNYATYHTLEEIYDFLDLLVAENPHLVSKIQIGN 150

  Fly   182 STQGNAIKGVKL-TSNANNKAIFIESGIHAREWISPAAATYIINQLLT--SQDPKVQQLAQDYNW 243
            :.:|..|..:|. |..:...||:|::|||:|||::.|:..:...::..  .||.....:....:.
Human   151 TYEGRPIYVLKFSTGGSKRPAIWIDTGIHSREWVTQASGVWFAKKITQDYGQDAAFTAILDTLDI 215

  Fly   244 IIFPCVNPDGYKYTFEHDRMWRKNRQ--LFGTCRGVDLNRNYPDHWNSTGSSSDPTRYDFAGPSA 306
            .:....||||:.:|...:|||||.|.  ....|.|||.|||:...:..:|:||:|....:.|..|
Human   216 FLEIVTNPDGFAFTHSTNRMWRKTRSHTAGSLCIGVDPNRNWDAGFGLSGASSNPCSETYHGKFA 280

  Fly   307 GSELETKRLIDFIRANAGKEQIKTYIALHSYSQMLMFPYGYTKERVSNYDDLQEFGKKASAAIKA 371
            .||:|.|.::||::.:.   .||.:|::|||||:||:||||..|.|.:.|:|.:..|.|..|:.:
Human   281 NSEVEVKSIVDFVKDHG---NIKAFISIHSYSQLLMYPYGYKTEPVPDQDELDQLSKAAVTALAS 342

  Fly   372 ENGRDYVSGSLFETIYPSSGGSMDWAHSEAGIPIAYTFELRGPPDSQDLFILPAVEIQPTASEAF 436
            ..|..:..||:.:.||.:||.::||.:|: ||..::|||||  ...:..|:|||.:|.|||.|.:
Human   343 LYGTKFNYGSIIKAIYQASGSTIDWTYSQ-GIKYSFTFELR--DTGRYGFLLPASQIIPTAKETW 404

  Fly   437 TAIRAIVEAAAEKGY 451
            .|:..|:|......|
Human   405 LALLTIMEHTLNHPY 419

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2915	NP_610338.1	Propep_M14	61..133	CDD:460505	9/72 (13%)
		M14_CP_A-B_like	154..444	CDD:349433	104/294 (35%)
CPA1	NP_001859.1	Propep_M14	26..100	CDD:460505	10/73 (14%)
		M14_CPA	117..417	CDD:349442	105/305 (34%)