DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment azot and SCGN

DIOPT Version :9

Sequence 1:	NP_610336.1	Gene:	azot / 35751	FlyBaseID:	FBgn0033238	Length:	148	Species:	Drosophila melanogaster
Sequence 2:	NP_008929.2	Gene:	SCGN / 10590	HGNCID:	16941	Length:	276	Species:	Homo sapiens

Alignment Length:	180	Identity:	40/180 - (22%)
Similarity:	76/180 - (42%)	Gaps:	34/180 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 DISHEERVLILD------TFRILDKDNEGAITSKEM-AVVIRALGRQPNDAEV---------QSM 51
            |.|.|..:..||      .::..|.|.:|.|..||: |..:..|.:...|..|         |..
Human     2 DSSREPTLGRLDAAGFWQVWQRFDADEKGYIEEKELDAFFLHMLMKLGTDDTVMKANLHKVKQQF 66

  Fly    52 INEVDSEGNGSIVAPEFCNVIL----------RKMRDTNHEDELREAFRIFDKDNNGYITTTELK 106
            :...|:..:|.|...|...:.|          |:....:...|..:.:|.:|.|::|:|:..||:
Human    67 MTTQDASKDGRIRMKELAGMFLSEDENFLLLFRRENPLDSSVEFMQIWRKYDADSSGFISAAELR 131

  Fly   107 NVFTALGV----KLSDDELEE----MIREYDLDQDNHLNYEEFVNMMTMR 148
            |....|.:    .:|:.:|||    |::.:|.::|..|:..:...::.::
Human   132 NFLRDLFLHHKKAISEAKLEEYTGTMMKIFDRNKDGRLDLNDLARILALQ 181

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
azot	NP_610336.1	PTZ00184	1..148	CDD:185504	40/178 (22%)
		EFh	12..72	CDD:238008	17/75 (23%)
		EFh	84..146	CDD:238008	18/69 (26%)
SCGN	NP_008929.2	EFh_HEF_SCGN	17..273	CDD:320078	35/165 (21%)
		EF-hand motif	17..45	CDD:320078	7/27 (26%)
		EF-hand motif	62..91	CDD:320078	6/28 (21%)
		EF-hand motif	109..138	CDD:320078	9/28 (32%)
		EF-hand motif	153..182	CDD:320078	4/29 (14%)
		EF-hand motif	201..230	CDD:320078
		EF-hand motif	245..273	CDD:320078
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910