Protein Alignment CG8728 and MAS2

DIOPT Version :9

• Sequence 1: NP_610333.1
• Gene: CG8728 / 35748
• FlyBaseID: FBgn0033235
• Length: 556
• Species: Drosophila melanogaster
• Sequence 2: NP_011889.1
• Gene: MAS2 / 856419
• SGDID: S000001066
• Length: 482
• Species: Saccharomyces cerevisiae
• Alignment Length: 455
• Identity: 164/455 - (36%)
• Similarity: 258/455 - (56%)
• Gaps: 37/455 - (8%)

  Fly    95 KVTTLPNGLRIASEPRYGQFCTVGLVIDSGPRYEVAYPSGVSHFLEKLAFNSTVNFPNKDAILKE 159
            |:::|.|||::|:....|.|..:||.||:|.|:|.....|.:|.|::|||.||.:...: |:.:.
Yeast    20 KLSSLANGLKVATSNTPGHFSALGLYIDAGSRFEGRNLKGCTHILDRLAFKSTEHVEGR-AMAET 83

  Fly   160 LEKNGGICDCQSSRDTLIYAASIDSRAIDSVTRLLADVTLRPTLSDQEVSLARRAVNFELETLGM 224
            ||..||...|.|||:.|:|.||:.::.:..:.:|:::....|.:::||:...:.:..:|::.:.|
Yeast    84 LELLGGNYQCTSSRENLMYQASVFNQDVGKMLQLMSETVRFPKITEQELQEQKLSAEYEIDEVWM 148

  Fly   225 RPEQEPILMDMIHAAAFRDNTLGLPKLCPLENLDHINRNVLMNYLKYHHSPKRMVIAGVGVDHDE 289
            :||.  :|.:::|.||:...|||.|.:||.|.:..|::..|::|....::|:..|.|.|||.|::
Yeast   149 KPEL--VLPELLHTAAYSGETLGSPLICPRELIPSISKYYLLDYRNKFYTPENTVAAFVGVPHEK 211

  Fly   290 LVSHVQRYFVEDKAIWETEALEDSGPKQVDTSIAQYTGGLVKEQCEIPIYAAAGLPELAHVILGF 354
            .:...::|..:    |:      |....:...:||||||   |.|..|......||||.|:.:||
Yeast   212 ALELTEKYLGD----WQ------STHPPITKKVAQYTGG---ESCIPPAPVFGNLPELFHIQIGF 263

  Fly   355 EGCSHQDKDFVPLCVLNIMMGGGGSFSAGGPGKGMYSRLYTKVLNRYHWMYSATAYNHAYGDCGL 419
            ||......|...|..|..::|||||||||||||||||||||.|||:|:::.:..|:||:|.|.|:
Yeast   264 EGLPIDHPDIYALATLQTLLGGGGSFSAGGPGKGMYSRLYTHVLNQYYFVENCVAFNHSYSDSGI 328

  Fly   420 FCVHGSAPPQHMNDMVEVLTREMMGMAAEPG----REELMRSKIQLQSMLLMNLESRPVVFEDVG 480
            |.:..|..||.....|||:.::|....|...    .:|:.|:|.||:|.|||||||:.|..||:|
Yeast   329 FGISLSCIPQAAPQAVEVIAQQMYNTFANKDLRLTEDEVSRAKNQLKSSLLMNLESKLVELEDMG 393

  Fly   481 RQVLVTGQRKRPQHFIKEIESVTAADIQRVAQRLLSSPPSVAARGDIHNLPEMSHITNAVSGSGR 545
            ||||:.|::......|.:||.:...||.|||:.:.:                 .::.||.:|.||
Yeast   394 RQVLMHGRKIPVNEMISKIEDLKPDDISRVAEMIFT-----------------GNVNNAGNGKGR 441

  Fly   546  545
            Yeast   442  441

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8728	NP_610333.1	PqqL	76..532	CDD:223685	159/440 (36%)
		Peptidase_M16	104..253	CDD:279066	47/148 (32%)
		Peptidase_M16_C	259..461	CDD:282978	77/205 (38%)
MAS2	NP_011889.1	PqqL	7..457	CDD:223685	164/455 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157345511
Domainoid	1	1.000	138	1.000	Domainoid score	I1054
eggNOG	1	0.900	-	-		E1_COG0612
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H6078
Inparanoid	1	1.050	285	1.000	Inparanoid score	I544
Isobase	1	0.950	-	0	Normalized mean entropy	S1277
OMA	1	1.010	-	-		QHG53769
OrthoFinder	1	1.000	-	-		FOG0003938
OrthoInspector	1	1.000	-	-		oto99384
orthoMCL	1	0.900	-	-		OOG6_102381
Panther	1	1.100	-	-	LDO	PTHR11851
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2194
SonicParanoid	1	1.000	-	-		X2236
TreeFam	1	0.960	-	-
	16	15.740